[Seminar] From Low resolution to High resolution Mass Spectrometry towards unequivocal identification.
When |
31 Oct, 2017
from
02:00 pm to 05:00 pm |
---|---|
Where | Auditorium |
Add event to your calendar | iCal |
Title: From Low resolution to High resolution mass Spectrometry towards unequivocal identification - Dancing with Ions through time and space.
Speaker: Daniel Ettlin (UNICAM) and Silvia Maia (FCUP)
Seminar organized within ONEIDA project
Host: Isabel Abreu, Uni-MS
Program
14:30 - 15:45 |
Conference 1 Title: From Low resolution to High resolution mass Spectrometry towards unequivocal identification. Subtitle : Dancing with Ions through time and space. Speaker: Daniel Ettlin - Unicam Sistemas Analiticos |
15:45 - 16:00 | Coffee Break |
16:00 - 17:00 |
Conference 2 Title : Applications using Orbitrap Analyser , a collection of experiences Speaker: Silvia Maia – Faculdade de Ciencias da Universidade do Porto |
Abstract Conference 1:
The number of users and areas of specialization in mass spectrometry has increased enormously in recent years. In the world of small molecules and Proteins, the new analytical procedures require sensitivity, selectivity and robustness within a short analysis time. Several different types of mass spectrometers are available, each one with their specific strengths and drawbacks. The decision on which one to use is usually based on the quality of the data combined to cost/time of the analysis.
Different types of "traditional" Mass Analyzers, like Triple Quads, Ion Trap, and Linear Traps will be presented. We will discuss the instrumental arrangements, its advantages, features and disadvantages in Quantitation and qualifying the molecules.
Recent publications have shown that high resolution mass spectrometry is a well-accepted and better alternative to the analysis molecules. There is a high need to add the possibility to perform data dependent MS2 experiments by making use of a resolving power of up to 140,000 FWHM. On that way, the mass analyzer Orbitrap represents one of the best alternatives currently available in the market [1]. This mass analyzer was first described in 2000 and has now reached the status of a mainstream mass spectrometry technique as it can support a wide range of applications from routine compound identification to the analysis of trace-level components in complex matrices
This presentation will discuss the application and use of the different technologies with some examples that will show the features of the different technologies.
[1] M. Kellmann, H. Muenster, P.Zomer, H. Mol, J. Am. Soc. Mass Spectrom, 2009, 20, 1464-1476.