MPS NOVA Kick-off Meeting
European Hub of Excellence in Microphysiological Systems
| When |
07 Nov, 2024 09:00 AM
to
08 Nov, 2024 05:00 PM |
|---|---|
| Where | ITQB NOVA Auditorium |
| Contact Name | Sarela Santamarina |
| Contact Email | sarela.santamarina@itqb.unl.pt |
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MPS NOVA is a TWINNING proposal led by the Instituto de Tecnologia Química e Biológica (ITQB NOVA) in collaboration with NOVA Medical School (NMS). MPS NOVA aims to establish a European Hub of Excellence in Microphysiological Systems (MPS) fuelled by pluripotent stem cell technologies to strengthen UNL´s Research and Innovation capacity.
MPS NOVA is centered on two key pillars:
I. the study of mechanisms of chronic diseases
II. the study of mechanisms of host-microbe interactions.
MPS NOVA brings together (i) in-house strong expertise in diverse biomedical research models at UNL; (ii) pioneering research in MPS systems at Universitätsklinikum Jena (UKJ, Germany); (iii) cutting-edge pluripotent stem cell technologies at Fondazione Human Technopole (FHT, Italy), and (iv) advanced integrative metabolomics and proteomics adapted to MPS at the Max Delbrück Center for Molecular Medicine (MDC, Germany).
download MPS_NOVA Program.pdf
Day 1 - Nov 7th – ITQB NOVA |
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| 09:00 | Management Check-In – Welcome Meet and Greet (8th floor) |
| 09:30 | Management meeting of MPS_NOVA Consortium (8th floor) (includes Coffee break) |
| 12:30 | Management Lunch (8th floor) |
| 13:00 | Participants Check-In (ITQB NOVA front desk) |
| 14:00 | MPS_NOVA Twinning Opening Raquel Sá Leão (ITQB Vice-Dean) |
| 14:10 | MPS_NOVA general introduction Sarela Santamarina, Cláudia Santos |
Session: Partners’ expertise in Microphysiological Systems |
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| Chairs: Sarela Santamarina, Cláudia Santos | |
| 14:30 | Organ-on-Chip for Dissecting Mechanisms of Host-Pathogen Interaction Alexander Mosig, UKJ |
| 15:15 | Organoids to Model Human Brain Development and Brain Diseases Agnieszka Rybak-Wolf, MDC |
| 16:00 | The First Italian Platform for Disease Modelling Giovanni Faga, Jacopo Zasso, FHT |
| 16:45 | Coffee break & Poster Session |
| 17:15 | State-of-art knowledge in Organ-on-Chip for Chronic Diseases, Host-Microbe Interactions Research, and the Translational Potential of MPS and Stem Cells in Therapeutic Developments. Leads: Alexander Mosig, UKJ Participants: Elena Martínez, Martin Raasch, Inês Figueira, Paul Wilmes |
| 18:30 | Cocktail & Poster Session |
| 20:00 | Dinner at Casa da Dizima, Paço de Arcos |
Day 2 – Nov 8th – ITQB NOVA |
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Session: Brains in a Dish: Organoids & Chips |
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Chair: Miguel Seabra, NOVA Medical School |
|
| 09:00 | Participants Check-In |
| 09:30 | Twinning on MPS to determine how Alzheimer’s-linked Endosomal Trafficking Defects cause Synapse Dysfunction Claudia Almeida, NOVA Medical School |
| 09:45 | MPS for disclosing Molecular Nutrition Benefits toward Brain Health Inês Figueira, NOVA Medical School |
| 10:00 | Exploring Carotid Body Connections using MPS Fatima Martins, NOVA Medical School |
| 10:15 | Advancing Chronic Disease Research through MPS_NOVA: Bridging Drosophila and Human Models Catarina Homem, NOVA Medical School |
| 10:30 | Innate Immune Microenvironments in Disease and Therapeutic Response Catarina Brito, ITQB NOVA |
| 10:45 | Advancing Retinal Disease Models Through Retinal Organoids Sandra Tenreiro, NOVA Medical School |
| 11:00 | Coffee break & Poster Session |
Session: Advances in Skin Microphysiological Systems |
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| Chair: Cristina Silva Pereira, ITQB NOVA | |
| 11:30 | Staphylococci and Skin Interactions during Health and Disease Maria Miragaia, ITQB NOVA |
| 11:45 | Reconstructed Skin Models in Pigmentation and Cutaneous Melanoma Research Duarte Barral, NOVA Medical School |
| 12:00 | 3D-Reconstructed Human Epidermis Models: towards more Realistic Environments for developing Antimicrobials that preserve a Balanced Skin Microbiome Ana Coelho, ITQB NOVA |
| 12:15 | Controlling Aspergillus Fumigatus Core Endohyphal Bacteria to Hinder the Fungal Host Pathogenicity Cristina Silva Pereira, ITQB NOVA |
| 12:30 | Lunch, room 2.13 |
Session: Advances in Microphysiological Systems for Other Organs |
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Chair: Duarte Barral, NOVA Medical School |
|
| 14:00 | Potential application of the organ-on-chip platform for testing new therapeutic strategies in Breast Cancer by targeting immunosuppressive neutrophils Guadalupe Cabral, NOVA Medical School |
| 14:15 | Novel model systems to study the interaction between Bilophila wadsworthia and the host Andreia Pimenta, ITQB NOVA |
| 14:30 | Clostridioides difficile spores are toxin delivery vehicles Adriano Henriques, ITQB NOVA |
| 14:45 | Exploring host-microbe interactions with Listeria monocytogenes using microphysiological systems José Andrade, ITQB NOVA |
| 15:00 | Human Liver Organoids for Investigating Inflammation in Chronic Metabolic Liver Disease Michel Kranendonk, NOVA Medical School |
| 15:15 | Using Nasopharyngeal Organoids to Study Streptococcus pneumoniae Colonization, Viral Interactions, and Biofilm Formation Raquel Sá-Leão, ITQB NOVA |
| 15:30 | Coffee Break |
Advisory Board Round Table |
|
| Chairs: Cláudia Santos, Sarela Santamarina | |
| 16:00 | Bruno Pereira, i3S Porto, Portugal Elena Martínez, IBEC, Spain Martin Raasch, Dynamic 42, Germany Paula Alves, IBET, Portugal Paul Wilmes, University of Luxembourg |
| 17:00 | Closing Remarks |
