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Compartmentalising enzymes in bacteria

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Martin Warren University of Kent-UK

When 08 Jul, 2009 from
11:00 am to 12:00 pm
Where Room 2.13
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Seminar

 

Title: Compartmentalising enzymes in bacteria

Speaker: Martin Warren

Affiliation: Department of Biosciences, University of Kent, UK

Host: Lígia Saraiva- Molecular Genetics of Microbial Resistance Laboratory

 

Abstract:

Prof. Martin Warren is Professor of Biochemistry at the University of Kent, UK, where he studies Tetrapyrrole Biosynthesis in bacteria, archaea and plants, and has been giving an essential contribution to the elucidation of the function/structure of several intermediates of this pathway. Moreover, Prof Warren develops research in the area of Scientific-Historiography where he showed that the enzymes of tetrapyrrole biosynthesis have influenced History. In fact, “lead poisoning, which affects the enzyme aminolaevulinic acid dehydratase, has been blamed for the fall of the Roman Empire, the calamitous Franklin expedition to the arctic and the Devonshire colic” (Prof. Warren’s quotation). Importantly, he proved that George III who suffered from porphyria, known as the “Madness of King George III”, resulted from mutations in porphobilinogen deaminase enzyme. This disease was transmitted through Queen Victoria into the British and German Royal families.

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