Micro-evolution, transmission and clonal replacement in MRSA - HOUR CHANGE
Edward Feil University of Bath, UK
When |
08 May, 2013
from
03:00 pm to 04:30 pm |
---|---|
Where | Auditorium |
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ITQB Seminar
Title: Micro-evolution, transmission and clonal replacement in MRSA.
Speaker: Edward Feil
Affiliation: Department of Biology and Biochemistry, University of Bath, UK
Host: Maria Miragaia PhD, Auxiliary Researcher
Laboratory of Molecular Genetics-ITQB
Abstract:
Next-generation sequencing (NGS) is providing detailed insights into the localised epidemiology of single clones and is set to dramatically improve our capacity at detecting and managing outbreaks. These data are also providing evidence concerning short term genetic changes and how these might relate to shifts in epidemiology. I will discuss recent work on NGS data for MRSA which illustrates how genetic changes are productively considered within epidemiological and phylogeographic contexts, and how genetic changes can be identified which lead to the emergence, and possible subsequent decline, of clinically relevant clones.