Mixing Methodologies in Single-use Bioreactors- A Comparative Analysis of Consistency Across Scale
Brian Lee MD PhD President, PBS Biotech, Inc
| When |
04 Apr, 2011
from
12:00 pm to 01:00 pm |
|---|---|
| Where | Auditorium |
| Add event to your calendar |
iCal
|
ITQB – IBET SEMINAR
Title: Mixing Methodologies in Single-use Bioreactors- A Comparative Analysis of Consistency Across Scale
Speaker: Brian Lee MD PhD
Affiliation: PBS Biotech, Inc - California, USA
Host: Manuel Carrondo
Abstract:
A lack of physiological environment consistency within the single-use cell culture bioreactor / vessel from bench scale to production scale is a limitation in scale-up efficiency. High variability in vessel geometry, mixing pattern, shear force and mass transfer rate of various bioreactors complicates process control through scale up. Presentation of comparative data will both reveal current inconsistencies and support an innovative solution for the future of biomanufacturing.
