Novel, single-use bioreactors using a pneumatic mixing mechanism
Brian Lee, PBS Biotech, USA
| When |
30 Oct, 2009
from
12:00 pm to 01:00 pm |
|---|---|
| Where | Auditorium |
| Add event to your calendar |
iCal
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Seminar
Title: Novel, single-use bioreactors using a pneumatic mixing mechanism
Speaker: Brian Lee
Affiliation: PBS Biotech, Inc. Camarillo, CA, USA
Host: Manuel Carrondo
Abstract:
PBS Biotech has developed an innovative bioreactor platform that employs a pneumatic mixing mechanism to convert the buoyancy of inlet gas bubbles into rotational energy, achieving efficient liquid/gas mixing without the need for any complicated external mechanical devices. This next generation disposable bioreactor is compact, easy-to-use, and scalable from 2 to 5,000 L. Due to this unprecedented scalability and consistent mixing performance across all volumes using the same mixing mechanism, a bench top unit can serve as a representative scale-down model for early-stage process development and for characterization of large-scale bioreactors. In this presentation, the mixing characteristics of these pneumatic bioreactors will be discussed including physical tests, computational fluid dynamics (CFD), and biological evaluation up to the 250 L scale.
About PBS Biotech
PBS Biotech develops, manufactures, and distributes a novel, single-use bioreactor system for biopharmaceutical R&D, pilot, and GMP manufacturing applications. We are a rapidly growing start-up company headquartered in the biotech corridor of Southern California, with additional offices in Michigan. We are proud of our team of talented and experienced bioprocess and quality assurance professionals who have had previous careers with leading biotech and equipment companies.
