[SCAN] Bioprocess Engineering for Vaccines Production
António Roldão, Engineering Cellular Application, ACT Unit, ITQB NOVA
| When |
01 Feb, 2017
from
12:00 pm to 01:00 pm |
|---|---|
| Where | Auditorium |
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Title: Bioprocess Engineering for Vaccines Production
Speaker: António Roldão
Affiliation: Engineering Cellular Application, Health & Pharma Division, ACT Unit, ITQB NOVA
Abstract:
The majority of novel protein-based biologics require animal cell technology for discovery and production. The costs and complexity associated to these production platforms are commonly high making mandatory further improvements in product yields. Technological breakthroughs and/or new producer hosts allied to classical systems/molecular biology tools and engineering methodologies are therefore necessary for accelerating biologics manufacturing process.
In this seminar two case studies will be presented where bioprocess engineering has been assisting vaccines production, namely:
- Case study 1. “Universal” Influenza VLP-based vaccine produced using the insect cells-baculovirus system
- Case study 2. Bioprocess engineering of Gag-VLPs using stable insect cells
Acknowledgements: This work was supported by EU-funded project EDUFLUVAC (FP7-HEALTH-2013-INNOVATION) and by Fundação para a Ciência e a Tecnologia (FCT; Portugal) through an FCT Investigator Starting Grant (IF/01704/2014).
