[SCAN] Insertion sequences as key players in phenotypic and genotypic plasticity of Staphylococcus haemolyticus
Ons Bouchami, Bacterial Evolution and Molecular Epidemiology, ITQB NOVA
When |
19 Apr, 2017
from
12:00 pm to 01:00 pm |
---|---|
Where | Auditorium |
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Title: Insertion sequences as key players in phenotypic and genotypic plasticity of Staphylococcus haemolyticus
Speaker: Ons Bouchami
Affiliation: Maria Miragaia Lab - Bacterial Evolution and Molecular Epidemiology
Abstract:
Staphylococcus haemolyticus is nowadays recognized as one of the most important nosocomial human pathogens worldwide, mainly associated to medical device-related infections. Our most recent approaches using whole genome sequencing have shown that cell populations of these bacteria suffer frequently phenotypic variation and genome rearrangements promoted by the activity of insertion sequences (IS) elements. The maintenance of subpopulations of cells in different physiological states might be a strategy to adapt rapidly to environmental stresses imposed by host or hospital environment.