UH Publications

A novel druggable interprotomer pocket in the capsid of rhino- and enteroviruses
Abdelnabi R, Geraets JA, Ma Y, Mirabelli C, Flatt JW, Domanska A, Delang L, Jochmans D, Kumar TA, Jayaprakash V, Sinha BN, Leyssen P, Butcher SJ, Neyts J

PLoS Biology, 2019; 17: 3000281.

Tick-borne encephalitis virus: a structural view. 
Pulkkinen LIA, Butcher SJ, Anastasina M. 
Viruses, 2018; 10:350. 

Genomic RNA folding mediates assembly of human parechovirus.
Shakeel S, Dykeman EC, White SJ, Ora A, Cockburn J, Butcher SJ, Stockley PG, Twarock R. 
Nature Communications, 2017; 8:5. 

Multiple capsid-stabilizing interactions revealed in a high-resolution structure of an emerging picornavirus causing neonatal sepsis.
Shakeel S, Westerhuis BM, Domanska A, Konig RI, Matadeen R, Koster AJ, Bakker AQ, Beaumont T, Wolthers KC, Butcher SJ.  
Nature Communications, 2016; 7:11387. 

A 3D cellular context for the macromolecular world.
Patwardhan A, Ashton A, Brandt R, Butcher S, Carzaniga R, Chiu W, Collinson L, Doux P, Duke E, Ellisman M, Franken E, Grünewald K, Heriche J, Koster A, Kühlbrandt W, Lagerstedt I, Larabell C, Lawson CL, Saibil HR, Sanz-García E, Subramaniam S, Verkade P, Swedlow JR, Kleywegt GJ. 
Nat. Struct. Mol. Biol., 2014; 21:841-845.

Architecture of respiratory syncytial virus revealed by electron cryotomography.
Liljeroos L, Krzyzaniak M, Helenius A, Butcher SJ (2013),
PNAS, 2013; 110:11133-11138.

Coagulation factor x activates innate immunity to human species c adenovirus.
Doronin K, Flatt JW, Di Paolo NC, Khare R, Kalyuzhniy O, Acchione M, Sumida JP, Ohto U, Shimizu T, Akashi-Takamura S, Miyake K, MacDonald JW, Bammler TK, Beyer RP, Farin FM, Stewart PL, Shayakhmetov DM.     Science 2012; 338, 795-798.

A mechanism for initiating RNA-dependent RNA polymerization. 
Butcher SJ, Grimes JM, Makeyev EV, Bamford DH and Stuart DI                                                                               Nature, 2001; 410:235-240.