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Book Chapters and Invited Manuscripts

2020

  • Pinto C, Estrada M, Brito C. 2020. In vitro and ex vivo models - the tumor microenvironment in a flask. Serpa J. (eds) Tumor microenvironment: the main driver of metabolic adaptation. Advances in Experimental Medicine and Biology, vol 1219. Springer. DOI:10.1007/978-3-030-34025-4_23.
  • Silva RJS, Mendes JP, Carrondo MJT, Alves PM, Peixoto C. 2020. Continuous Chromatography Purification of Virus-Based Biopharmaceuticals: A Shortcut Design Method. Animal Cell Biotechnology. Humana, New York, NY. 367-384. DOI:10.1007/978-1-0716-0191-4_21.

2019

  • Rebelo SP, Pinto C, Lopes N, Martins T, Alves PM, Brito C. 2019. 3D-3-Culture: Tumor Models to Study Heterotypic Interactions in the Tumor Microenvironment. Tan T. (eds) Immuno-Oncology: Cellular and Translational Approaches. Methods in Pharmacology and Toxicology, Humana Press, New York, NY. DOI:10.1007/978-1-0716-0171-6_8.
  • Isidro IA, Pais DAM, Alves PM, Carrondo MJT. 2018. Online Control Strategies, Comprehensive Biotechnology 3rd edition. DOI:10.1016/B978-0-444-64046-8.00112-9.

2018

  • Sebastião, M.J.*, Abecasis, B.*, Carrondo M. JT., Alves, P., Gomes-Alves, P., Serra, M.. 2018. 3D strategies for expansion of human cardiac progenitor cells, In: Bioreactors For Stem Cell Expansion and Differentiation. CRC Press Taylor & Francis Group, Florida.
  • Vidic S, Estrada MF, Gjerde K, Santo VE, Osswald A, Barbier M, Chong Y, Sommergruber W, de Hoogt, Brito C, Graeser R. 2018. PREDECT protocols for complex 2D/3D cultures. Ziegler S., Waldmann H. (eds) Systems Chemical Biology. Methods in Molecular Biology, vol 1888. Humana Press, New York, NY. DOI:10.1007/978-1-4939-8891-4_1.

2016

  • Fernandes P, Silva AC, Coroadinha AS, Alves PM. 2016. Upstream Bioprocess for Adenovirus Vectors. In: David T. Curiel (Ed.), Adenoviral Vectors for Gene Therapy, Academic Press, 2nd Edition, Elsevier. DOI:10.1016/B978-0-12-800276-6.00006-1.

2015

  • Silva AC, Roldão A, Teixeira A, Fernandes P, Sousa MFQ, Alves PM 2015. Cell Immobilization for the Production of Viral Vaccines. In: Al-Rubeai M. (eds) Animal Cell Culture. Cell Engineering, vol 9. Springer, Cham. DOI:10.1007/978-3-319-10320-4_17.
  • Rebelo SP, Costa R, Sousa MF, Brito C, Alves PM. 2015. Establishing Liver Bioreactors for In Vitro Research. Methods Mol Biol. 1250:189-202. DOI:10.1007/978-1-4939-2074-7_13.

2014

  • Fernandes F, Teixeira AP, Carinhas N, Carrondo MJT, Alves PM. 2014. Production of complex virus-like particles in Insect cells. Future Medicine, January 2014, Pages 120-134. DOI:10.2217/fmeb2013.13.67.
  • Duarte T, Carinhas N, Silva AC, Alves PM, Teixeira AP. 2014. 1H-NMR protocol for exometabolome analysis of cultured mammalian cells. In: Pörtner, Ralf (Ed.), Animal Cell Biotechnology - Methods and Protocols, Methods in Molecular Biology, 3rd Edition, Springer, 1104, 237-247. DOI:10.1007/978-1-62703-733-4_16.
  • Vidigal J, Fernandes F, Coroadinha AS, Teixeira AP, Alves PM. 2014. Insect cell line development using Flp-mediated cassette exchange technology. In: Pörtner, Ralf (Ed.), Animal Cell Biotechnology - Methods and Protocols, Methods in Molecular Biology, 3rd Edition, Springer, 1104:15-27. DOI:10.1007/978-1-62703-733-4_2.
  • Silva AC, Fernandes P, Sousa MFQ, and Alves PM. 2014.  “Scalable production of adenovirus vectors” In: Adenovirus – Methods and Protocols, Chillón, Miguel; Bosch, Assumpció (Eds.), Series: Methods in Molecular Biology, Volume 1089, p. 175-196 3rd Edition, Springer, DOI:10.1007/978-1-62703-679-5_13.
  • Rebelo S, Costa R, Sousa M, Brito C, Alves PM. 2014. Establishing liver bioreactors for in vitro research - M Vinken, and V Rogiers (eds.),  Protocols in in vitro hepatocyte research, Springer Science. DOI:10.1007/978-1-4939-2074-7_13.

2013

  • Simplício AL, Coroadinha AS, Gilmer JF, Lamego J. 2013. A Methodology for Detection and Quantification of Esterase Activity. In: Volpi N., Maccari F. (eds) Capillary Electrophoresis of Biomolecules. Methods in Molecular Biology (Methods and Protocols), vol 984. Humana Press, Totowa, NJ. DOI: 10.1007/978-1-62703-296-4_22.
  • Tomás H, Rodrigues AF, Alves PM and Coroadinha AS. 2013. ‘Lentiviral gene therapy vectors: challenges and future directions’ In ‘Gene Therapy - Tools and Potential Applications, Dr. Francisco Martin (Ed.), ISBN: 978-953-51-1014-9, InTech, DOI:10.5772/52534.
  • Serra M, Correia C, Brito C and Alves PM. 2013. “Bioprocessing of Human Pluripotent Stem Cells for Cell Therapy Applications” - Chapter 4, M. Al-Rubeai, M. Naciri (eds.), Stem Cells and Cell Therapy, Cell Engineering 8, Springer Science, DOI:10.1007/978-94-007-7196-3_4.
  • Correia C, Espinha N, Brito C, Serra M, Alves PM. 2013. Bioengenharia de células estaminais pluripotentes humanas para aplicação clínica. Boletim Biotecnologia 4, 31-33. (in Portuguese).
  • Simão D, Pinto C, Serra M, Brito C, Alves PM. 2013. Sistemas de cultura 3D para diferenciação neural de células estaminais humanas. Boletim Biotecnologia 4, 17-20. (in Portuguese).

2012

  • Coroadinha AS, Wirth D, Rodrigues AF, Gama-Norton L, Duros C, Cohen-Haguenauer O, Alves PM, Cruz PE, Carrondo MJT, Hauser H. 2012. Modular retroviral producer cell lines In ‘The CliniBook: Clinical gene transfer’ Edited by Odile Cohen-Haguenauer – EDK, Paris.
  • Bandeira V, Peixoto C, Coroadinha AS, Cruz PE, Carrondo MJT, Merten O-W, Alves PM. 2012. Facing the challenges of downstream processing of lentiviral vectors In ‘The CliniBook: Clinical gene transfer’ Edited by Odile Cohen-Haguenauer – EDK, Paris.
  • Silva AC, Simão D, Sousa MFQ, Peixoto C, Cruz PE, Carrondo MJT, and Alves PM. 2012. “Production and purification of Ad vectors: current status and future needs for Adenovirus vector production” In: Odile Cohen-Haguenauer – EDK, Paris (ed.), The CliniBook - Clinical Gene transfer state of the art, pp. 245-252, ISBN: 2842541715, EDP Sciences.

2011

  • Cruz PE, Rodrigues T, Carmo M, Dagmar W, Amaral AI, Alves PM, Coroadinha AS. 2011. Manufacturing of Retroviruses. In: Merten OW., Al-Rubeai M. (eds) Viral Vectors for Gene Therapy. Methods in Molecular Biology (Methods and Protocols), vol 737. Humana Press. DOI: 10.1007/978-1-61779-095-9_7.
  • Teixeira AP, Oliveira R, Alves PM, and Carrondo MJT. 2011. Process Considerations | Online Control Strategies. In: Murray Moo-Young (ed.), Comprehensive Biotechnology, Second Edition, volume 2, pp. 875–882. Elsevier.
  • Roldão A., Silva AC, Mellado MCM, Alves PM, and Carrondo MJT. 2011. Viruses and Virus-Like Particles in Biotechnology: Fundamentals and Applications. In: Murray Moo-Young (ed.), Comprehensive Biotechnology, Second Edition, volume 1, pp. 625–649. Elsevier. DOI:10.1016/B978-0-12-809633-8.09046-4.
  • Rodrigues AF, Alves PM, Coroadinha AS. 2011. Production of Retroviral and Lentiviral Gene Therapy Vectors: Challenges in the Manufacturing of Lipid Enveloped Virus, Viral Gene Therapy, Ke Xu (Ed.), ISBN: 978-953-307-539-6, InTech Publisher. DOI:10.5772/18615.
  • Vicente T, Peixoto C, Mota JPB, Carrondo MJT, Alves PM. 2011. Optimizing Downstream Processing of Enveloped Viruses: Case Study Demonstrates Utility of Novel Strategies, Genetic Engineering & Biotechnology News: Bioprocess Tutorial January 15.

2010

  • Serra M, Brito C, Alves PM. 2010. Bioengineering strategies for stem cell expansion and differentiation, Canal Bioquímica, 7:30-37.

2009

  • Vicente T, Peixoto C, Carrondo MJT, and Alves PM. 2009. “Virus production for clinical gene therapy” in W. Walther and U. Stein (Eds.), “Methods in Molecular Medicine – Cancer Gene Therapy”, second edition, Humana Press, Totowa, NJ, USA. DOI:10.1007/978-1-59745-561-9_24.

2008

  • Mello I, Conceição MM, Jorge S, Cruz PE, Alves PM, Carrondo MJT and Pereira CA. 2008. “Viral vaccines: concepts, principles and bioprocesses” in Castilho, LR, Moraes, AM, Augusto, EFP, Butler M (Eds.), "Animal Cell Technology – from biopharmaceuticals to Gene Therapy", Taylor & Francis, London, UK.
  • Mello I, Conceição MM, Jorge S, Cruz PE, Alves PM, Carrondo MJT and Pereira CA. 2008. “Vacinas virais: Conceitos, princípios e Bioprocessos” in Moraes AM, Augusto EFP, Castilho LR (Eds.), "Tecnologia do Cultivo de Células Animais: de Biofármacos a Terapia Gênica", Taylor & Francis, São Paulo, Brazil.
  • Alves PM, Cruz PE, Carrondo MJT. 2008. “Introdução à Tecnologia de Cultivo de Células Animais” in Moraes, AM, Augusto, EFP, Castilho, LR (Eds.), "Tecnologia de Cultivo de Células Animais: de Biofármacos a Terapia Gênica", Taylor & Francis, São Paulo, Brazil.
  • Alves PM, Carrondo MJT, Cruz PE. 2008. “Introduction to Animal Cell Technology” in Leda R. Castilho, Angela Moraes, Elisabeth F. P. Augusto, Michael Butler (Ed.), “Animal Cell technology: from Biopharmaceuticals to Gene Therapy”, Taylor & Francis, Abingdon, UK.

2007

  • Cruz PE, Carmo M, Rodrigues T, Alves PM. 2007. “Retrovirus production and characterization” in Ralf Pörtner (Ed.), “Animal Cell Biotechnology - Methods and protocols”, Humana Press, Totowa, NJ, USA. DOI:10.1007/978-1-59745-399-8_22.

2003

  • Moreira JL, Miranda PM, Alves PM, Marcelino I, Carrondo MJ. 2003. Culture methods for mass production of ruminant endothelial cells. Fermentation Biotechnology, 862, Chapter 8:124-41. Oxford. DOI:10.1021/bk-2003-0862.ch008.
  • Carrondo MJT, Cruz PE, Gonçalves LD, Maranga L and Moreira JL. 2003. “Terapia génica e novas vacinas” in N. Lima and M. Mota (Eds.), “Biotecnologia, fundamentos e aplicações”, Lidel, Lisboa, Portugal.

2001

  • Barbotin JN, Portais JC, Alves PM, Santos H. 2001. NMR and immobilized cells. Immobilized cells - Springer Lab Manuals, 261:54. ISBN 978-3-540-67070-4. DOI:10.1007/978-3-642-56891-6_12.

1999

  • Mueller P, Carvalhal AV, Moreira JL, Geserick C, Schroeder K, Carrondo MJ, Hauser H. 1999. Development of an IRF-1 based proliferation control system. Cell Engineering, 1:220-38. Kluwer Academic Publishers. DOI:10.1007/978-0-585-37971-5_8.

1997

  • Alves PM, MJ Carrondo, H Santos. 1997. Immobilization of primary brain cells in porous microcarriers for on-line NMR spectroscopy. Animal Cell Technology: From Vaccines to Genetic Medicine:91-98. Kluwer Academic Publishers. DOI:10.1007/978-94-011-5404-8_15.

1995

  • Moreira JL, Gonçalves L, Alves PM, Cruz PE, Santos H, Carrondo MJ. 1995. Aplicações de células animais em biotecnologia. Boletim de biotecnologia 51: 5-14.
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