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2012

2012

  1. Tostões R, Leite SB, Serra M, Jensen J, Björquist P, Carrondo MJ, Brito C, Alves PM, 2012. Human liver cell spheroids in extended perfusion bioreactor culture for repeated dose drug testing. Hepatology, 55(4): 1227-36. http://dx.doi.org/10.1002/hep.24760
  2. Serra M, Brito C, Correia C, Alves PM, 2012. Process engineering human pluripotent stem cells for clinical applications. Trends Biotechnol, 30(6):350-9. http://dx.doi.org/10.1016/j.tibtech.2012.03.003
  3. Carinhas N, Oliveira R, Alves PM, Carrondo MJ, Teixeira AP, 2012. Systems biotechnology of animal cells: the road to prediction. Trends Biotechnol, 30(7):377-85 http://dx.doi.org/10.1016/j.tibtech.2012.03.004
  4. Monteiro F, Carinhas N, Carrondo MJT, Bernal V and Alves PM, 2012. Toward system-level understanding of baculovirus–host cell interactions: from molecular fundamental studies to large-scale proteomics approaches. Front. Microb. doi: 10.3389/fmicb.2012.00391. http://www.frontiersin.org/Virology/10.3389/fmicb.2012.00391/full
  5. Roldão A, Mellado MC, Lima JC, Carrondo MJ, Alves PM, Oliveira R, 2012. On the effect of thermodynamic equilibrium on the assembly efficiency of complex multi-layered virus-like particles (VLP): the case of rotavirus VLP. PLoS Comput Biol, 8(2): e1002367. http://dx.doi.org/10.1371/journal.pcbi.1002367
  6. Almeida AS, Queiroga CS, Sousa MF, Alves PM, Vieira HL, 2012. Carbon monoxide modulates apoptosis by reinforcing oxidative metabolism in astrocytes: role of BCL-2. J Biol Chem, 287 (14): 10761-70. http://dx.doi.org/10.1074/jbc.M111.306738
  7. Brito C, Simão D, Costa I, Malpique R, Pereira CI, Fernandes P, Serra M, Schwarz SC, Schwarz J, Kremer EJ, Alves PM, 2012. Generation and genetic modification of 3D cultures of human dopaminergic neurons derived from neural progenitor cells. Methods, 56(3):452-60. http://dx.doi.org/10.1016/j.ymeth.2012.03.005
  8. Bandeira V, Peixoto C, Rodrigues AF, Cruz PE, Alves PM, Coroadinha AS, Carrondo MJ, 2012. Downstream processing of lentiviral vectors: releasing bottlenecks. Hum Gene Ther Methods, 23(4):255-63. http://dx.doi.org/10.1089/hgtb.2012.059
  9. Leite SB, Wilk-Zasadna I, Zaldivar Comenges JM, Airola E, Reis-Fernandes MA, Mennecozzi M, Guguen-Guillouzo C, Chesne C, Gouillou C, Alves PM, Coecke S, 2012. 3D HepaRG model as an attractive tool for toxicity testing. Toxicol Sci, Epub ahead of print http://dx.doi.org/10.1093/toxsci/kfs232
  10. Queiroga CS, Tomasi S, Wideroe M, Alves PM, Vercelli A, Vieira HL, 2012. Preconditioning triggered by Carbon Monoxide (CO) provides neuronal protection following perinatal hypoxia-ischemia. Plos One, 7(8): e42632. http://dx.doi.org/10.1371/journal.pone.0042632
  11. Fernandes F, Vidigal J, Dias M, Prather KL, Coroadinha AS, Teixeira AP, Alves PM, 2012. Flipase-mediated cassette exchange in Sf9 insect cells for stable gene expression. Biotechnol Bioeng, 109(11):2836-44. http://dx.doi.org/10.1002/bit.24542
  12. Rodrigues AF, Amaral AI, Veríssimo V, Alves PM, Coroadinha AS, 2012. Adaptation of retrovirus producer cells to serum deprivation: Implications in lipid biosynthesis and vector production. Biotechnol Bioeng, 109 (5): 1269-79. http://dx.doi.org/10.1002/bit.24410
  13. Malpique R, Tostões R, Beier AF, Serra M, Brito C, Schulz JC, Björquist P, Zimmermann H, Alves PM, 2012. Surface-based cryopreservation strategies for human embryonic stem cells: A comparative study. Biotechnol Prog, 28(4):1079-87. http://dx.doi.org/10.1002/btpr.1572
  14. Marcelino I, Almeida AM, Brito C, Meyer D, Barreto M, Sheikboudou C, Franco CF, Martinez D, Lefrançois T, Vachiéry N, Carrondo MJ, Coelho A, Alves PM, 2012. Proteomic analyses of Ehrlichia ruminantium highlight differential expression of MAP1-family proteins. Vet Microbiol, 156 (2012) 305–314. http://dx.doi.org/10.1016/j.vetmic.2011.11.022
  15. Carrondo MJ, Alves PM, Carinhas N, Glassey J, Hesse F, Merten OW, Micheletti M, Noll T, Oliveira R, Reichl U, Staby A, Teixeira AP, Weichert H, Mandenius CF, 2012. How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology? Biotechnol J, Epub ahead of print. http://dx.doi.org/10.1002/biot.201200226
  16. Tavares L, Figueira I, McDougall GJ, Vieira HL, Stewart D, Alves PM, Ferreira RB, Santos CN, 2012. Neuroprotective effects of digested polyphenols from wild blackberry species. Eur J Nutr. http://dx.doi.org/10.1007/s00394-012-0307-7
  17. Queiroga CS, Almeida AS and Vieira HL, 2012. Carbon monoxide targeting mitochondria. Biochem Res Int, 2012:749845. http://dx.doi.org/10.1155/2012/749845

 

 


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