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2016

  1. Carvalho SB, Freire JM, Moleirinho MG, Monteiro F, Gaspar D, Castanho MA, Carrondo MJ, Alves PM, Bernardes GJ, Peixoto C. 2016. Bioorthogonal Strategy for Bioprocessing of Specific-Site-Functionalized Enveloped Influenza-Virus-Like Particles. Bioconjugate Chemistry. 2386–2399. https://doi.org/10.1021/acs.bioconjchem.6b00372
  2. Santo VE, Babo P, Amador M, Correia C, Cunha B, Coutinho DF, Neves NM, Mano JF, Reis RL, Gomes ME. 2016. Engineering Enriched Microenvironments with Gradients of Platelet Lysate in Hydrogel Fibers.  Biomacromolecules.  13;17(6):1985-97 https://doi.org/10.1021/acs.biomac.6b00150
  3. Simão D, Terrasso AP, Teixeira AP, Brito C, Sonnewald U, Alves PM .  2016.  Functional metabolic interactions of human neuron-astrocyte 3D in vitro networks.  Scientific Reports .  6, 33285.  http://dx.doi.org/10.1038/srep33285
  4. Gomes-Alves P, Serra M, Brito C, Ricardo CP, Cunha R, Sousa MF, Sanchez B, Bernad A, Carrondo MJT, Rodriguez-Borlado L, Alves PM. 2016. In vitro expansion of human cardiac progenitor cells: exploring 'omics tools for characterization of cell-based allogeneic products. Translational Research. http://www.sciencedirect.com/science/article/pii/S1931524416000554
  5. Correia C, Koshkin A, Carido M, Espinha N, Šarić T, Lima PA, Serra M, Alves PM. 2016. Effective Hypothermic Storage of Human Pluripotent Stem Cell-Derived Cardiomyocytes Compatible With Global Distribution of Cells for Clinical Applications and Toxicology Testing. Stem Cells Transl Med. http://stemcellstm.alphamedpress.org/content/early/2016/03/25/sctm.2015-0238.full.pdf
  6. Monteiro F, Bernal V, Chaillet, M, Berger I, Alves PM.  2016.  Targeted supplementation design for improved production and quality of enveloped viral particles in insect cell-baculovirus expression system.  Journal of Biotechnology.  10;233:34-41.  http://dx.doi.org/10.1016/j.jbiotec.2016.06.029
  7. Silva AC, Teixeira AP, Alves PM. 2016. Impact of Adenovirus infection in host cell metabolism evaluated by 1H NMR spectroscopy. J Biotechnol. http://dx.doi.org/10.1016/j.jbiotec.2016.05.025
  8. Carinhas N, Pais DAM, Koshkin A, Fernandes P, Coroadinha A, Carrondo MJT, Alves PM, Teixeira AP. 2016. Metabolic flux profilling of MDCK cells during growth and canine adenovirus vector production. Scientific Reports 6: 23529. http://www.nature.com/articles/srep23529
  9. Isidro IA, Portela RM, Clemente JJ, Cunha AE, Oliveira R. 2016. Hybrid metabolic flux analysis and recombinant protein prediction in Pichia pastoris X-33 cultures expressing a single-chain antibody fragment.  Bioprocess Biosyst Eng.  39(9):1351-63. https://doi.org/10.1007/s00449-016-1611-z
  10. Stock K, Estrada MF, Vidic S, Gjerde K, Rudisch A, Santo VE, Barbier M, Blom S, Arundkar SC, Selvam I, Osswald A, Stein Y, Gruenewald S, Brito C, van Weerden W, Rotter V, Boghaert E, Oren M, Sommergruber W, Chong Y, de Hoogt R, Graeser R. 2016. Capturing tumor complexity in vitro: Comparative analysis of 2D and 3D tumor models for drug discovery. Scientific Reports. 6, 28951.  http://dx.doi.org/10.1038/srep28951
  11. Almeida AS, Sonnewald U, Alves PM, Vieira HL. 2016. Carbon monoxide improves neuronal differentiation and yield by increasing the functioning and number of mitochondria. J Neurochem.  138(3):423-35. https://doi.org/10.1111/jnc.13653
  12. Almeida AS, Soares NL, Vieira M, Gramsbergen JB, Vieira HL. 2016. Carbon Monoxide Releasing Molecule-A1 (CORM-A1) Improves Neurogenesis: Increase of Neuronal Differentiation Yield by Preventing Cell Death.  PLoS One.  11(5):e0154781.  https://doi.org/10.1371/journal.pone.0154781
  13. Kleiderman S, Gutbier S, Ugur Tufekci K, Ortega F, Sá JV, Teixeira AP, Brito C, Glaab E, Berninger B, Alves PM, Leist M. 2016. Conversion of Nonproliferating Astrocytes into Neurogenic Neural Stem Cells: Control by FGF2 and Interferon-γ.  Stem Cells. https://doi.org/10.1002/stem.2483
  14. Barbier M, Jaensch S, Cornelissen F, Vidic S, Gjerde K, de Hoogt R, Graeser R, Gustin E, Chong YT; Hickman J, Burbridge M, Verschuren E, Kallioniemi O, Klefström J, Brisken C, Rotter V, Oren M, Brito C, Schalken J, Jenster G, van Weerden W, Vilo J, Schueler J, Monni O, Barry ST, Grünewald S, Kallio P, Mueller H, Nopora A, Sommergruber W, Anderson E, van der Kuip H, Smalley M,  Boghaert E. .  2016.  Ellipsoid Segmentation Model for Analyzing Light-Attenuated 3D Confocal Image Stacks of Fluorescent Multi-Cellular Spheroids.  PLoS One .  11, e0156942. http://dx.doi.org/10.1371/journal.pone.0156942
  15. Fernandes CS, Castro R, Coroadinha AS, Roque AC. 2016. Small synthetic ligands for the enrichment of viral particles pseudotyped with amphotropic murine leukemia virus envelope. J Chromatogr A. pii: S0021-9673(16)30125-X. http://dx.doi.org/10.1016/j.chroma.2016.02.026
  16. Santo VE, Estrada MF, Rebelo SP, Abreu S, Silva I, Pinto C, Veloso SC, Serra AT, Boghaert E, Alves PM, Brito, C. 2016. Adaptable stirred-tank culture strategies for large scale production of multicellular spheroid-based tumor cell models. J Biotechnol. 221 118-29. http://dx.doi.org/10.1016/j.jbiotec.2016.01.031
  17. Perdigao-Henriques R, Petrocca F, Altschuler G, Thomas MP, Le MT, Tan SM, Hide W, Lieberman J.  2016.  miR-200 promotes the mesenchymal to epithelial transition by suppressing multiple members of the Zeb2 and Snail1 transcriptional repressor complexes.  Oncogene.  35 (2): 158-72. http://dx.doi.org/10.1038/onc.2015.69
  18. Soares HR, Castro R, Tomas HA, Rodrigues AF, Gomes-Alves P, Bellier B, Klatzmann D, Carrondo MJ, Alves PM, Coroadinha AS. 2016. Tetraspanins displayed in retrovirus-derived virus-like particles and their immunogenicity. Vaccine. http://dx.doi.org/10.1016/j.vaccine.2015.12.015
  19. Estrada MF, Rebelo SP, Davies EJ, Pinto MT, Pereira H, Santo VE, Matthew J. Smalley, Barry ST, Gualda EJ, Alves PM, Anderson E, Brito C. 2016. Modelling the tumor microenvironment in long-term microencapsulated 3D cocultures recapitulates phenotypic features of disease progression. Biomaterials. http://dx.doi.org/10.1016/j.biomaterials.2015.11.030
  20. Patrone M, Coroadinha AS, Teixeira AP, Alves PM. 2016. Palmitoylation strengthens cholesterol-dependent multimerization and fusion activity of human cytomegalovirus gB. Journal of Biochemical Chemistry. http://dx.doi.org/10.1074/jbc.M115.682252
  21. Alves, M., Lamego, J., Bandeiras, T., Castro, R., Tomas, H., Coroadinha, A.S., Costa, J., and Simplício, A.L. 2016. Human Carboxylesterase 2: studies on the role of glycosylation for enzymatic activity. Biochem Biophy Rep 5, 105-10. http://dx.doi.org/10.1016/j.bbrep.2015.11.018
  22. Cunha B, Silva RJ, Aguiar T, Serra M, Daicic J, Maloisel JL, Clachan J, Åkerblom A, Carrondo MJ, Peixoto C, Alves PM. 2016. Improving washing strategies of human mesenchymal stem cells using negative mode expanded bed chromatography. J Chromatogr A. 2016 Jan 15;1429:292-303. http://dx.doi.org/10.1016/j.chroma.2015.12.052
  23. Simao D, Pinto C, Fernandes P, Piersanti S, Saggio I, Collinson LM, Schiavo G, Kremer EJ, Alves PM & Brito C. 2016. Evaluation of helper-dependent canine adenovirus vectors in a 3D human CNS model. Gene Therapy, 23(1):86-94 http://dx.doi.org/10.1038/gt.2015.75
  24. Kleiderman S, Sá JV, Teixeira AP, Brito C, Gutbier S, Evje LG, Hadera MG, Glaab E, Henry M, Sachinidis A, Alves PM, Sonnewald U, Leist M. 2016. Functional and phenotypic differences of pure populations of stem cell-derived astrocytes and neuronal precursor cells. Glia. May;64(5):695-715. https://doi.org/10.1002/glia.22954
     
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