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2017

  1. Carvalho SB, Moleirinho MG, Wheatley D, et al. Universal label-free in-process quantification of influenza virus-like particles. Biotechnol J. 2017;12(8). doi:10.1002/biot.201700031.

  2. Correia C, Koshkin A, Duarte P, et al. Distinct carbon sources affect structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells. Sci Rep. 2017;7(8590). doi:10.1038/s41598-017-08713-4.

  3. Cunha B, Silva RJS, Correia C, et al. Finding the design space of a filtration-based operation for the concentration of human pluripotent stem cells. J Memb Sci. 2017;542(August):399-407. doi:10.1016/j.memsci.2017.08.036.

  4. Gonçalves M, De Carvalho M, Peixoto C, et al. Phosphoneurofilament heavy chain and vascular endothelial growth factor as cerebrospinal fluid biomarkers for ALS. Amyotroph Lateral Scler Front Degener. 2017. doi:10.1080/21678421.2016.1212894.

  5. Figueira I, Tavares L, Jardim C, et al. Blood–brain barrier transport and neuroprotective potential of blackberry-digested polyphenols: an in vitro study. Eur J Nutr. 2017. doi:10.1007/s00394-017-1576-y.

  6. Figueira I, Garcia G, Pimpão RC, et al. Polyphenols journey through blood-brain barrier towards neuronal protection. Sci Rep. 2017;7(1):1-16. doi:10.1038/s41598-017-11512-6.

  7. B Carvalho S, Fortuna AR, Wolff MW, et al. Purification of influenza virus-like particles using sulfated cellulose membrane adsorbers. J Chem Technol Biotechnol. 2017;93(7). doi:10.1002/jctb.5474.

  8. De Hoogt R, Estrada MF, Vidic S, et al. Protocols and characterization data for 2d, 3d, and slice-based tumor models from the predect project. Sci Data. 2017;4(170170). doi:10.1038/sdata.2017.170.

  9. Lamy M, Ferreira A, Dias JS, Braga S, Silva G, Barbas A. Notch-out for breast cancer therapies. N Biotechnol. 2017;39(August):215-221. doi:10.1016/j.nbt.2017.08.004.

  10. Boghaert ER, Lu X, Hessler PE, et al. The Volume of Three-Dimensional Cultures of Cancer Cells In Vitro Influences Transcriptional Profile Differences and Similarities with Monolayer Cultures and Xenografted Tumors. Neoplasia (United States). 2017;19(9):695-706. doi:10.1016/j.neo.2017.06.004.

  11. Terrasso AP, Silva AC, Filipe A, et al. Human neuron-astrocyte 3D co-culture-based assay for evaluation of neuroprotective compounds. J Pharmacol Toxicol Methods. 2017;Jan-Fev(83):72-79. doi:10.1016/j.vascn.2016.10.001.

  12. Bandeira VS, Tomás HA, Alici E, Carrondo MJT, Coroadinha AS. Disclosing the Parameters Leading to High Productivity of Retroviral Producer Cells Lines: Evaluating Random Versus Targeted Integration. Hum Gene Ther Methods. 2017;28(2):78-90. doi:10.1089/hgtb.2016.149.

  13. Monteiro F, Bernal V, Alves PM. The role of host cell physiology in the productivity of the baculovirus-insect cell system: Fluxome analysis of Trichoplusia ni and Spodoptera frugiperda cell lines. Biotechnol Bioeng. 2017;114(3):674-684. doi:10.1002/bit.26089.

  14. Teixeira AP, Fussenegger M. Synthetic biology-inspired therapies for metabolic diseases. Curr Opin Biotechnol. 2017;Oct(47):59-66. doi:10.1016/j.copbio.2017.06.004.

  15. Wilson JL, Bouillaud F, Almeida AS, et al. Carbon monoxide reverses the metabolic adaptation of microglia cells to an inflammatory stimulus. Free Radic Biol Med. 2017;Mar(104):311-323. doi:10.1016/j.freeradbiomed.2017.01.022.

  16. Torán JL, Aguilar S, López JA, et al. CXCL6 is an important paracrine factor in the pro-angiogenic human cardiac progenitor-like cell secretome. Sci Rep. 2017;7(12490). doi:10.1038/s41598-017-11976-6.

  17. Cunha B, Aguiar T, Carvalho SB, et al. Bioprocess integration for human mesenchymal stem cells: From up to downstream processing scale-up to cell proteome characterization. J Biotechnol. 2017;Apr(248):87-98. doi:10.1016/j.jbiotec.2017.01.014.

  18. Abecasis B, Aguiar T, Arnault É, et al. Expansion of 3D human induced pluripotent stem cell aggregates in bioreactors: Bioprocess intensification and scaling-up approaches. J Biotechnol. 2017;Mar(246):81-93. doi:10.1016/j.jbiotec.2017.01.004.

  19. Gouveia PJ, Rosa S, Ricotti L, et al. Flexible nanofilms coated with aligned piezoelectric microfibers preserve the contractility of cardiomyocytes. Biomaterials. 2017;Sep(139):213-228. doi:10.1016/j.biomaterials.2017.05.048.

  20. Sá J V., Kleiderman S, Brito C, et al. Quantification of Metabolic Rearrangements During Neural Stem Cells Differentiation into Astrocytes by Metabolic Flux Analysis. Neurochem Res. 2017;42(1):244-253. doi:10.1007/s11064-016-1907-z.

  21. Santo VE, Rebelo SP, Estrada MF, Alves PM, Boghaert E, Brito C. Drug screening in 3D in vitro tumor models: overcoming current pitfalls of efficacy read-outs. Biotechnol J. 2017;12(1):1-18. doi:10.1002/biot.201600505.

  22. Vilaça R , Barros I , Matmati N , Silva E, Martins T, Teixeira V ,  Hannun YA, Costa V. The ceramide activated protein phosphatase Sit4 impairs sphingolipid dynamics, mitochondrial function and lifespan in a yeast model of Niemann-Pick type C1. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. https://doi.org/10.1016/j.bbadis.2017.10.010

  23. Almeida, A.S., Vieira, H.L.A. 2017. Role of Cell Metabolism and Mitochondrial Function During Adult Neurogenesis. Neurochem Res 42, 1787–1794. https://doi.org/10.1007/s11064-016-2150-3

  24. Carinhas N, Koshkin A, Pais DA, Alves PM, Teixeira AP. 2017. 13 C-metabolic flux analysis of human adenovirus infection: Implications for viral vector production. Biotechnol Bioeng. Jan;114(1):195-207. https://doi.org/10.1002/bit.26063

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