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Publications

Publications 

 

  • S. Pires, J. Habjanič, M. Sezer, C. M. Soares, L. Hemmingsen, O. Iranzo. “Design of a peptidic turn with high affinity for Hg(II)”. Inorg. Chem., 2012, 51, 11339−11348.
  • S. Chakraborty, O. Iranzo, E. Zuiderweg and V. L. Pecoraro. "An Experimental and Theoretical Evaluation of Multi-site Cd(II) Exchange in Designed Three-Stranded Coiled Coil Peptides". J. Am. Chem. Soc., 2012, 134, 6191–6203.
  • O. Iranzo, “Manganese complexes displaying Superoxide Dismutase activity: a balance between different factors”. Bioorganic Chem., 2011, 39, 73-87.
  • O. Iranzo, S. Chakraborty, L. Hemmingsen and V. L. Pecoraro. “Controlling and Fine Tuning the Physical Properties of Two Identical Metal Coordination Sites in De Novo Designed Three Stranded Coiled Coil Peptides”. J. Am. Chem. Soc., 2011, 133, 239-251.
  • O. Iranzo, T. Jakusch, K-H Lee, L. Hemmingsen and V. L. Pecoraro. “The Correlation of 113Cd NMR and 111mCd PAC Spectroscopies Provides a Powerful Approach for the Characterization of the Structure of CdII -Substituted ZnII Proteins”. Chem. Eur. J., 2009, 15, 3761-3772.
  • A. F. A. Peacock, O. Iranzo, and V. L. Pecoraro. “Harnessing natures ability to control metal ion coordination geometry using de novo designed peptides”. Dalton Trans. , 2009, 2271-2280.
  • T. Humphry, S. Iyer, O. Iranzo, J. R. Morrow, J. P. Richard, P. Paneth and A.C. Hengge. "Altered Transition State for the Reaction of an RNA Model Catalyzed by a Dinuclear Zinc(II) Catalyst". J. Am. Chem. Soc. , 2008, 130, 17858-17866.
  • O. Iranzo, P. V. Thulstrup, S-B. Ryu, L. Hemmingsen and V. L. Pecoraro. “The application of 199Hg NMR and 199mHg PAC Spectroscopies to Define the Biological Chemistry of Hg(II): A Case Study Using Designed Two and Three Stranded Coiled Coils”. Chem. Eur. J., 2007, 13, 9178-9190. 
  • O. Iranzo, C. Cabello and V. L. Pecoraro. “Heterochromia in Designed Metallopeptides: Geometry-Selective Binding of Cd(II) in a De Novo Peptide”. Angew. Chem. Int. Ed., 2007, 46, 6688-6691.  
  • O. Iranzo, D. Ghosh and V. L. Pecoraro. “Assessing the integrity of designed homomeric parallel 3-stranded coiled coils in the presence of metal ions”. Inorg. Chem., 2006, 45, 9959-9973.
  • M-Y. Yang, O. Iranzo, J. P. Richard and J. R. Morrow. “Solvent Deuterium Isotope Effects on Phosphodiester Cleavage Catalyzed by an Extraordinarily Active Zn(II) Complex”. J. Am. Chem. Soc. 2005, 127, 1064-1065.
  • J. R. Morrow and O. Iranzo. “Synthetic Metallonucleases for RNA Cleavage”, Curr. Opin. Chem. Biol. , 2004, 8, 192-200.
  • O. Iranzo, H. Khalili, D. M. Epstein and J. R. Morrow. "Recruitment of Divalent Metal Ions by Incorporation of 4-Thio-2’-deoxythymidine or 4-Thio-2’-deoxyuridine into DNA”, J. Biol. Inorg. Chem., 2004, 9, 462-470.
  • O. Iranzo, J. P. Richard and J. R. Morrow. "Structure-Activity Studies on the Cleavage of an RNA Analog by a Potent Dinuclear Metal Ion Catalyst: Effect of Changing the Metal Ion”, Inorg. Chem., 2004, 43, 1743-1750.
  • O. Iranzo, T. Elmer, J. P. Richard and J. R. Morrow. “Cooperativity between Metal Ions in the Cleavage of Phosphate Diesters and RNA by Dinuclear Zn(II) Catalysts”, Inorg. Chem. 2003, 42, 7737-7746. 
  • O. Iranzo, A. Y. Kovalevsky, J. R. Morrow and J. P. Richard. "Physical and Kinetic Analysis of the Cooperative Role of Metal Ions in Catalysis of Phosphodiester Cleavage by a Dinuclear Zn(II) Complex", J. Am. Chem. Soc. 2003, 125, 1988-1993.
  • L. Huang, L. L. Chappell, O. Iranzo, B. F. Baker and J. R. Morrow. "Oligonucleotide conjugates of Eu (III) tetraaza macrocycles with pendent alcohol and amide groups promote sequence-specific RNA cleavage", J. Biol. Inorg. Chem. 2000, 5:85-92.

 

Book chapters

 

  • V. L. Pecoraro, A. F. A. Peacock, O. Iranzo, M. Luczkowski, “Understanding the Biological Chemistry of Mercury Using a de novo Protein Design Strategy”, ACS Symposium Series, Vol. 1012, Bioinorganic Chemistry, Chapter 12, pp 183–197 (DOI: 10.1021/bk-2009-1012.ch012).

           

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