2003-2004

2004

• PROTEIN STABILIZATION BY OSMOLYTES FROM HYPERTHERMOPHILES: EFFECT OF MANNOSYLGLYCERATE ON THERMAL UNFOLDING OF SNase STUDIED BY PICOSECOND TIME-RESOLVED FLUORESCENCE AND CALORIMETRY
  T. Q. Faria, J. C. Lima, M. Bastos, A. L. Maçanita & H. Santos
  The Journal of Biological Chemistry, 279, 48680-48691(2004). 
   
• UNFOLDING OF UBIQUITIN STUDIED BY PICOSECOND TIME-RESOLVED FUORESCENCE OF THE TYROSINE RESIDUE
  M. Noronha, J. C. Lima, M. Bastos, H. Santos & A. L. Maçanita
  Biophysical Journal, 87, 2609-2620 (2004).
   
• INTRAMOLECULAR FLUORESCENCE QUENCHING OF TYROSINE BY THE PEPTIDE a-CARBONYL GROUP REVISITED
  M. Noronha, J. C. Lima, P. Lamosa, H. Santos, C. Maycock, R. Ventura & A. L. Maçanita
  Journal of Physical Chemistry A, 108, 2155-2166 (2004). 
   
• A GENE FROM THE MESOPHILIC BACTERIUM Dehalococcoides ethenogenes ENCODES A NOVEL MANNOSYLGLYCERATE SYNTHASE
  N. Empadinhas, L. Albuquerque, J. Costa, S. H. Zinder, M. A. S. Santos, H. Santos & M. S. da Costa
  Journal of Bacteriology, 186, 4075-4084 (2004). 
   
• SPECIALIZED ROLES OF THE TWO PATHWAYS FOR THE SYNTHESIS OF MANNOSYLGLYCERATE IN OSMOADAPTATION AND THERMOADAPTATION OF Rhodothermus marinus
  N. Borges, J. D. Marugg, N. Empadinhas, M. S. da Costa & H. Santos
  The Journal of Biological Chemistry, 279, 9892-9898 (2004).
   
• EFFECT OF PYRUVATE KINASE OVERPRODUCTION ON GLUCOSE METABOLISM OF Lactococcus lactis
  A. Ramos, A. R. Neves, R. Ventura, C. Maycock & H. Santos
  Microbiology-SGM, 150, 1103-1111 (2004).
   
• ENGINEERING Lactococcus lactis FOR THE PRODUCTION OF MANNITOL: HIGH YIELDS FROM FOOD-GRADE STRAINS DEFICIENT IN LACTATE DEHYDROGENASE AND THE MANNITOL TRANSPORT SYSTEM
  P. Gaspar, A. R. Neves, A. Ramos, M. J. Gasson, C. A. Shearman, & H. Santos
  Applied and Environmental Microbiology, 70, 1466-1474 (2004). 
   
• ENHANCEMENT OF TREHALOSE PRODUCTION IN DAIRY PROPIONIBACTERIA THROUGH MANIPULATION OF ENVIRONMENTAL CONDITIONS
  F. S. Cardoso, P. Gaspar, J. Hugenholtz, A. Ramos & H. Santos
  International Journal of Food Microbiology, 91, 195-204 (2004). 
  
   

2003

• YEAST LIFESPAN EXTENSION BY CALORIE RESTRICTION IS INDEPENDENT OF NAD FLUCTUATION
  R. M. Anderson, M. Latorre-Esteves, A. R. Neves, S. Lavu, O. Medvedik, C. Taylor, K. T. Howitz, H. Santos & D. A. Sinclair
  Science, 302, 2124-2126 (2003). 
   
• PROTEIN STABILISATION BY COMPATIBLE SOLUTES: EFFECT OF DIGLYCEROL PHOSPHATE ON THE DYNAMICS OF Desulfovibrio gigas RUBREDOXIN STUDIED BY NMR
  P. Lamosa, D. L. Turner, R. Ventura, C. Maycock & H. Santos
  European Journal of Biochemistry, 270, 4606-4614 (2003). 
   
• LYSINE-2,3-AMINOMUTASE AND ß-LYSINE ACETYLTRANSFERASE GENES OF METHANOGENIC ARCHAEA ARE SALT INDUCED AND ARE ESSENTIAL FOR THE BIOSYNTHESIS OF N-ACETYL- ß -LYSINE AND GROWTH AT HIGH SALINITY
  K. Pflüger, S. Baumann, G. Gottschalk, W. Lin, H. Santos & V. Müller
  Applied and Environmental Microbiology, 69, 6047-6055 (2003). 
   
• PROTEIN STABILISATION BY COMPATIBLE SOLUTES: EFFECT OF MANNOSYLGLYCERATE ON UNFOLDING THERMODYNAMICS AND ACTIVITY OF RIBONUCLEASE A
  T. Q. Faria, S. Knapp, R. Ladenstein, A. L. Maçanita & H. Santos
  ChemBioChem, 4, 734-741 (2003).
   
• CRYSTALLIZATION AND PRELIMINARY X-RAY CHARACTERIZATION OF CYTOCHROME c" FROM THE OBLIGATE METHYLOTROPH Methylophilus methylotrophus.
  F. J. Enguita, L. Rodrigues, M. Archer, L. Sieker, A. Rodrigues, E. Pohl, D. L. Turner, H. Santos & M. A. Carrondo
  Acta Crystallographica D Biological Crystallography, 59, 580-583 (2003).
   
• THE BACTERIUM Thermus thermophilus, LIKE HYPERTHERMOPHILIC ARCHAEA, USES A TWO-STEP PATHWAY FOR THE SYNTHESIS OF MANNOSYLGLYCERATE.
  N. Empadinhas, L. Albuquerque, A. Henne, H. Santos & Milton S. da Costa
  Applied and Environmental Microbiology, 69, 3272-3279 (2003). 
   
• RESPONSE OF A STRICT ANAEROBE TO OXYGEN: SURVIVAL STRATEGIES IN Desulfovibrio gigas
  P. Fareleira, B. S. Santos, C. António, P. Moradas Ferreira, J. LeGall, A. V. Xavier & H. Santos
  Microbiology, 149, 1513-1522 (2003).
   
• Salinisphaera shabanense GEN. NOV., SP. NOV., A NOVEL, MODERATELY HALOPHILIC BACTERIUM FROM THE BRINE-SEAWATER INTERFACE OF THE SHABAN DEEP, RED SEA
  Antunes, W. Eder, P. Fareleira, H. Santos & R. Huber
  Extremophiles, 7, 29-34 (2003). 
   
• A VARIANT OF THE HYPERTHERMOPHILE Archaeoglobus fulgidus ADAPTED TO GROW AT HIGH SALINITY
  L. G. Gonçalves, R. Huber, M. S. da Costa & H. Santos
  FEMS Letters, 218, 239-244 (2003).
   
• METABOLIC PATHWAY FOR PROPIONATE UTILISATION BY PHOSPHORUS ACCUMULATING ORGANISMS IN ACTIVATED SLUDGE: 13C-LABELLING AND IN VIVO NMR
  P. Lemos, C. Vieira, L. S. Serafim, M. M. Santos, M. A. M. Reis & H. Santos
  Applied and Environmental Microbiology, 69, 241-251 (2003).
   
• SYNTHESIS OF GDP MANNOSE AND MANNOSYLGLYCERATE FROM LABELED MANNOSE BY ENGINEERED Escherichia coli WITHOUT LOSS OF SPECIFIC ISOTOPIC ENRICHMENT
  M.-M. Sampaio, H. Santos & W. Boos
  Applied and Environmental Microbiology, 69, 233-240 (2003).