Publications
2024
- Structure-function mapping and mechanistic insights on the SARS CoV2 Nsp1.Protein Sci. 2024 Dec;33(12):e5228. doi: 10.1002/pro.5228.PMID: 39584680
- SARS-CoV2 Nsp1 is a metal-dependent DNA and RNA endonuclease. Biometals. 2024 Oct;37(5):1127-1146. doi: 10.1007/s10534-024-00596-z. Epub 2024 Mar 28.PMID: 38538957
- Biochemical, Biophysical, and Structural Analysis of an Unusual DyP from the ExtremophileDeinococcus radiodurans. Molecules. 2024 Jan 11;29(2):358. doi: 10.3390/molecules29020358.PMID: 38257271
- Structural insights into terminal arabinosylation biosynthesis of the mycobacterial cell wall arabinan.bioRxiv [Preprint]. 2024 Sep 18:2024.09.17.613533. doi: 10.1101/2024.09.17.613533.PMID: 39345558
- Pires C, Marques IJ, Saramago A, Moura MM, Pojo M, Cabrera R, Santos C, Rosário F, Lousa D, Vicente JB, Bandeiras TM, Teixeira MR, Leite V, Cavaco BM. Identification of novel candidate predisposing genes in familial nonmedullary thyroid carcinoma implicating DNA damage repair pathways. Int J Cancer. 2025 Jan 1;156(1):130-144. doi: 10.1002/ijc.35159. Epub 2024 Sep 9. PMID: 39251783
- Pires C, Marques IJ, Valério M, Saramago A, Santo PE, Santos S, Silva M, Moura MM, Matos J, Pereira T, Cabrera R, Lousa D, Leite V, Bandeiras TM, Vicente JB, Cavaco BM. CHEK2 germline variants identified in familial nonmedullary thyroid cancer lead to impaired protein structure and function. J Biol Chem. 2024 Mar;300(3):105767. doi: 10.1016/j.jbc.2024.105767. Epub 2024 Feb 16. PMID: 38367672
- Hipólito A, Xavier R, Brito C, Tomás A, Lemos I, Cabaço LC, Silva F, Oliva A, Barral DC, Vicente JB, Gonçalves LG, Pojo M, Serpa J. BRD9 status is a major contributor for cysteine metabolic remodeling through MST and EAAT3 modulation in malignant melanoma. Biochim Biophys Acta Mol Basis Dis. 2024 Feb;1870(2):166983. doi: 10.1016/j.bbadis.2023.166983. Epub 2023 Dec 7. PMID: 38070581
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Structure and function of Campylobacter jejuni polynucleotide phosphorylase (PNPase): Insights into the role of this RNase in pathogenicity. Biochimie. 2024 Jan;216:56-70. doi: 10.1016/j.biochi.2023.10.006. Epub 2023 Oct 6.PMID: 37806617
2023
- Fernandes A, Williamson A, Matias PM, Moe E. Structure/function studies of the NAD+-dependent DNA ligase from the poly-extremophile Deinococcus radiodurans reveal importance of the BRCT domain for DNA binding. Extremophiles. 2023 Sep 15;27(3):26. doi: 10.1007/s00792-023-01309-z. PMID: 37712998; PMCID: PMC10504179.
- Gouveia AG, Salgueiro BA, Ranmar DO, Antunes WDT, Kirchweger P, Golani O, Wolf SG, Elbaum M, Matias PM, Romão CV. Unraveling the multifaceted resilience of arsenic resistant bacterium Deinococcus indicus. Front Microbiol. 2023 Aug 24;14:1240798. doi: 10.3389/fmicb.2023.1240798. PMID: 37692390.
- Biocatalysis for biorefineries: The case of dye-decolorizing peroxidases.
Biotechnol Adv. 2023 Jul-Aug;65:108153. doi: 10.1016/j.biotechadv.2023.108153. Epub 2023 Apr 11.PMID: 37044267
- Conceição CJF, Salgueiro BA, Ribeiro PA, Raposo M, Moe E. Advances in the expression and purification of human PARP1: A user-friendly protocol. Protein Expr Purif. 2023 Nov;211:106336. doi: 10.1016/j.pep.2023.106336. Epub 2023 Jul 5. PMID: 37419399.
- Alves MMS, Melo MN, Mertens HDT, Pereiro AB, Archer M. Studies on the Interaction between Model Proteins and Fluorinated Ionic Liquids. Pharmaceutics. 2023 Jan 3;15(1):157. doi: 10.3390/pharmaceutics15010157. PMID: 36678790; PMCID: PMC9863861.
- Hipólito A, Mendes C, Martins F, Lemos I, Francisco I, Cunha F, Almodôvar T, Albuquerque C, Gonçalves LG, Bonifácio VDB, Vicente JB, Serpa J. H2S-Synthesizing Enzymes Are Putative Determinants in Lung Cancer Management toward Personalized Medicine. Antioxidants (Basel). 2023 Dec 28;13(1):51. doi: 10.3390/antiox13010051. PMID: 38247476
- Vicente JB, Guerreiro ACL, Felgueiras B, Chapla D, Tehrani D, Moremen KW, Costa J. Glycosyltransferase 8 domain-containing protein 1 (GLT8D1) is a UDP-dependent galactosyltransferase. Sci Rep. 2023 Dec 7;13(1):21684. doi: 10.1038/s41598-023-48605-4. PMID: 38066107
- Madeira CA, Anselmo C, Costa JM, Bonito CA, Ferreira RJ, Santos DJVA, Wanders RJ, Vicente JB, Ventura FV, Leandro P. Functional and structural impact of 10 ACADM missense mutations on human medium chain acyl-Coa dehydrogenase. Biochim Biophys Acta Mol Basis Dis. 2023 Oct;1869(7):166766. doi: 10.1016/j.bbadis.2023.166766. Epub 2023 May 29. PMID: 37257730
- Leandro P, Lino PR, Lopes R, Leandro J, Amaro MP, Sousa P, Vicente JB, Almeida AJ. Isothermal denaturation fluorimetry vs differential scanning fluorimetry as tools for screening of stabilizers for protein freeze-drying: Human phenylalanine hydroxylase as the case study. Eur J Pharm Biopharm. 2023 Jun;187:1-11. doi: 10.1016/j.ejpb.2023.03.012. Epub 2023 Apr 1. PMID: 37011788
- Insights into the role of three Endonuclease III enzymes for oxidative stress resistance in the extremely radiation resistant bacteriumDeinococcus radiodurans. Front Microbiol. 2023 Sep 12;14:1266785. doi: 10.3389/fmicb.2023.1266785. eCollection 2023.PMID: 37771704
- Structure/function studies of the NAD+-dependent DNA ligase from the poly-extremophile Deinococcus radiodurans reveal importance of the BRCT domain for DNA binding. Extremophiles. 2023 Sep 15;27(3):26. doi: 10.1007/s00792-023-01309-z.PMID: 37712998
- Advances in the expression and purification of human PARP1: A user-friendly protocol.
Protein Expr Purif. 2023 Nov;211:106336. doi: 10.1016/j.pep.2023.106336. Epub 2023 Jul 5.PMID: 37419399
- Liposome Formulations for the Strategic Delivery of PARP1 Inhibitors: Development and Optimization.
Nanomaterials (Basel). 2023 May 11;13(10):1613. doi: 10.3390/nano13101613.PMID: 37242030
2022
- Moe E, Silveira CM, Zuccarello L, Rollo F, Stelter M, De Bonis S, Kulka-Peschke C, Katz S, Hildebrandt P, Zebger I, Timmins J, Todorovic S. Human endonuclease III/NTH1: focusing on the [4Fe-4S] cluster and the N-terminal domain. Chem Commun (Camb). 2022 Nov 10;58(90):12568-12571. [doi: 10.1039/d2cc03643f. PMID: 36279116].
- Rollo F, Borges PT, Silveira CM, Rosa MTG, Todorovic S, Moe E. Disentangling Unusual Catalytic Properties and the Role of the [4Fe-4S] Cluster of Three Endonuclease III from the Extremophile D. radiodurans. Molecules. 2022 Jul 2;27(13):4270. doi: 10.3390/molecules27134270. PMID: 35807515; PMCID: PMC9268735.
- Silva LSO, Matias PM, Romão CV, Saraiva LM. Repair of Iron Center Proteins-A Different Class of Hemerythrin-like Proteins. Molecules. 2022 Jun 23;27(13):4051. doi: 10.3390/molecules27134051. PMID: 35807291; PMCID: PMC9268430.
- Alves, M. M. S., Leandro, P., Mertens, H. D. T., Pereiro, A. B., & Archer, M. (2022). Impact of Fluorinated Ionic Liquids on Human Phenylalanine Hydroxylase-A Potential Drug Delivery System. Nanomaterials (Basel, Switzerland), 12(6), 893. https://doi.org/10.3390/nano12060893
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Correia MJ, Pimpão AB, Fernandes DGF, Morello J, Sequeira CO, Calado J, Antunes AMM, Almeida MS, Branco P, Monteiro EC, Vicente JB, Serpa J, Pereira SA. Cysteine as a Multifaceted Player in Kidney, the Cysteine-Related Thiolome and Its Implications for Precision Medicine. Molecules. 2022 Feb 19;27(4):1416. doi: 10.3390/molecules27041416. PubMed PMID: 35209204; PubMed Central PMCID: PMCPMC8874463.
- Unveiling molecular details behind improved activity at neutral to alkaline pH of an engineered DyP-type peroxidase.
Comput Struct Biotechnol J. 2022 Jul 21;20:3899-3910. doi: 10.1016/j.csbj.2022.07.032. eCollection 2022.PMID: 35950185
2021
- Tan, M., Li, S., Juillard, F., Chitas, R., Custodio, T. F., Xue, H., Szymula, A., Sun, Q., Liu, B., Alvarez, A. L., Chen, S., Huang, J., Simas, J. P., McVey, C. E.* & Kaye, K. M.* (2021) MLL1 is regulated by KSHV LANA and is important for virus latency, Nucleic acids research. 49, 12895-12911. [10.1093/nar/gkab1094] * Corresponding authors
- Zuhra K, Tome CS, Forte E, Vicente JB, Giuffre A. The multifaceted roles of sulfane sulfur species in cancer-associated processes. Biochim Biophys Acta Bioenerg. 2021;1862(2):148338. Epub 2020/11/20. doi: 10.1016/j.bbabio.2020.148338. PubMed PMID: 33212042.
- Nunes SC, Ramos C, Santos I, Mendes C, Silva F, Vicente JB, et al. Cysteine Boosts Fitness Under Hypoxia-Mimicked Conditions in Ovarian Cancer by Metabolic Reprogramming. Front Cell Dev Biol. 2021;9:722412. Epub 2021/08/31. doi: 10.3389/fcell.2021.722412. PubMed PMID: 34458274; PubMed Central PMCID: PMCPMC8386479.
- Lopes RR, Tome CS, Russo R, Paterna R, Leandro J, Candeias NR, et al. Modulation of Human Phenylalanine Hydroxylase by 3-Hydroxyquinolin-2(1H)-One Derivatives. Biomolecules. 2021;11(3). Epub 2021/04/04. doi: 10.3390/biom11030462. PubMed PMID: 33808760; PubMed Central PMCID: PMCPMC8003416.
- Goncalves-Dias C, Sequeira CO, Vicente JB, Correia MJ, Coelho NR, Morello J, et al. A Mechanistic-Based and Non-invasive Approach to Quantify the Capability of Kidney to Detoxify Cysteine-Disulfides. Adv Exp Med Biol. 2021;1306:109-20. Epub 2021/05/08. doi: 10.1007/978-3-030-63908-2_8. PubMed PMID: 33959909.
- Fernandes DGF, Nunes J, Tome CS, Zuhra K, Costa JMF, Antunes AMM, et al. Human Cystathionine gamma-Lyase Is Inhibited by s-Nitrosation: A New Crosstalk Mechanism between NO and H(2)S. Antioxidants (Basel). 2021;10(9). Epub 2021/09/29. doi: 10.3390/antiox10091391. PubMed PMID: 34573023; PubMed Central PMCID: PMCPMC8467691.
- Amaral C, Vicente CT, Caetano SM, Gaspar-Cordeiro A, Yang Y, Cloetens P, Romão CV, Rodrigues-Pousada C, Pimentel C. An Internal Promoter Drives the Expression of a Truncated Form of CCC1 Capable of Protecting Yeast from Iron Toxicity. Microorganisms. 2021 Jun 20;9(6):1337. doi: 10.3390/microorganisms9061337. PMID: 34203091; PMCID: PMC8235630.
- Bonifacio VDB, Pereira SA, Serpa J, Vicente JB. Cysteine metabolic circuitries: druggable targets in cancer. Br J Cancer. 2021;124(5):862-79. Epub 2020/11/24. doi: 10.1038/s41416-020-01156-1. PubMed PMID: 33223534; PubMed Central PMCID: PMCPMC7921671.
2020
- Silveira CM, Moe E, Fraaije M, Martins LO, Todorovic S. Resonance Raman view of the active site architecture in bacterial DyP-type peroxidases. RSC Adv. 2020 Mar 17;10(19):11095-11104. doi: 10.1039/d0ra00950d. PMID: 35495352; PMCID: PMC9050505.
- Carvalho LAR, Almeida VT, Brito JA, Lum KM, Oliveira TF, Guedes RC, Gonçalves LM, Lucas SD, Cravatt BF, Archer M, Moreira R. 3-Oxo-β-sultam as a Sulfonylating Chemotype for Inhibition of Serine Hydrolases and Activity-Based Protein Profiling. ACS Chem Biol. 2020 Apr 17;15(4):878-883. doi: 10.1021/acschembio.0c00090. Epub 2020 Mar 20. PMID: 32176480.
2019
- Tome CS, Lopes RR, Sousa PMF, Amaro MP, Leandro J, Mertens HDT, et al. Author Correction: Structure of full-length wild-type human phenylalanine hydroxylase by small angle X-ray scattering reveals substrate-induced conformational stability. Sci Rep. 2019;9(1):17513. Epub 2019/11/21. doi: 10.1038/s41598-019-54425-2. PubMed PMID: 31745241; PubMed Central PMCID: PMCPMC6863894.
- Tome CS, Lopes RR, Sousa PMF, Amaro MP, Leandro J, Mertens HDT, et al. Structure of full-length wild-type human phenylalanine hydroxylase by small angle X-ray scattering reveals substrate-induced conformational stability. Sci Rep. 2019;9(1):13615. Epub 2019/09/22. doi: 10.1038/s41598-019-49944-x. PubMed PMID: 31541188; PubMed Central PMCID: PMCPMC6754429.
- Santos I, Ramos C, Mendes C, Sequeira CO, Tome CS, Fernandes DGH, et al. Targeting Glutathione and Cystathionine beta-Synthase in Ovarian Cancer Treatment by Selenium-Chrysin Polyurea Dendrimer Nanoformulation. Nutrients. 2019;11(10). Epub 2019/10/23. doi: 10.3390/nu11102523. PubMed PMID: 31635026; PubMed Central PMCID: PMCPMC6836284.
- Malagrino F, Zuhra K, Mascolo L, Mastronicola D, Vicente JB, Forte E, et al. Hydrogen Sulfide Oxidation: Adaptive Changes in Mitochondria of SW480 Colorectal Cancer Cells upon Exposure to Hypoxia. Oxid Med Cell Longev. 2019;2019:8102936. Epub 2019/03/07. doi: 10.1155/2019/8102936. PubMed PMID: 30838088; PubMed Central PMCID: PMCPMC6374825.
2018
- Pires de Miranda M, Quendera AP, McVey CE, Kaye KM, Simas JP. (2018) "In Vivo Persistence of Chimeric Virus after Substitution of the Kaposi's Sarcoma-Associated Herpesvirus LANA DNA Binding Domain with That of Murid Herpesvirus 4." J Virol. 92(21). pii: e01251-18. doi: [10.1128/JVI.01251-18]
- M.C. Almadanim, N.M. Gonçalves, M.T.G. Rosa, B.M. Alexandre, A.M. Cordeiro, M. Rodrigues, N.J. Saibo, C.M. Soares, C.V. Romão, M. Oliveira, and I.A. Abreu I. (2018) "The rice cold-responsive calcium-dependent protein kinase OsCPK17 is regulated by alternative splicing and post-translational modifications" BBA- Mol Cell Res 1865 (2): 231-246.
http://doi.org/10.1016/j.bbamcr.2017.10.010 - C. da Silveira Tomé, A.E. Foucher, J.M. Jault, D. Housset (2017) "High concentrations of GTP induce conformational changes in the essential bacterial GTPase EngA and enhance its binding to the ribosome", FEBS J 285(1):160-177.
http://10.1111/febs.14333
2017
- F.M. Sousa, F.V. Sena, A.P. Batista, D. Athayde, J.A. Brito, M. Archer, A.S.F. Oliveira, C.M. Soares, T. Catarino, and M.M. Pereira (2017) "The key role of glutamate 172 in the mechanism of type II NADH:quinone oxidoreductase of Staphylococcus aureus", Biochim Biophys Acta 1858(10): 823-832.
http://dx.doi.org/10.1016/j.bbabio.2017.08.002 - A.C. Habison, M.P. de Miranda, C. Beauchemin, M. Tan, S.A. Cerqueira, B. Correia, R. Ponnusamy, E.J. Usherwood, C.E. McVey, J.P. Simas, and K.M. Kaye (2017) "Cross-species conservation of episome maintenance provides a basis for in vivo investigation of Kaposi's sarcoma herpesvirus LANA", PLoS Pathog 13(9): e1006555.
http://dx.doi.org/10.1371/journal.ppat.1006555 - E. Moe, F. Rollo, C.M. Silveira, M. Sezer, P. Hildebrandt, and S. Todorovic (2017) "Spectroelectrochemical insights into structural and redox properties of immobilized endonuclease III and its catalytically inactive mutant", Spectrochim Acta A Mol Biomol Spectrosc, in press
http://dx.doi.org/10.1016/j.saa.2017.06.050 - L. Pereira, I.H. Saraiva, A.S.F. Oliveira, C.M. Soares, R.O. Louro, and Frazão C (2017) "Molecular structure of FoxE, the putative iron oxidase of Rhodobacter ferrooxidans SW2", Biochim Biophys Acta 1858(10):847-853.
http://dx.doi.org/10.1016/j.bbabio.2017.07.002 - M. Alves, N.S.M. Vieira, L.P.N. Rebelo, J.M.M. Araújo, A.B. Pereiro, and M. Archer (2017) "Fluorinated ionic liquids for protein drug delivery systems: Investigating their impact on the structure and function of lysozyme", Int J Pharm 526(1-2): 309-320.
http://dx.doi.org/10.1016/j.ijpharm.2017.05.002 - M.C. Marques, C. Tapia, O. Gutiérrez-Sanz, A.R. Ramos, K.L. Keller, J.D. Wall, A.L. De Lacey, P.M. Matias, and I.A.C. Pereira (2017) "The direct role of selenocysteine in [NiFeSe] hydrogenase maturation and catalysis", Nat Chem Biol 13(5): 544-550.
http://dx.doi.org/10.1038/nchembio.2335 - E. Forte, V.B. Borisov, J.B. Vicente, and A. Giuffrè (2017) "Cytochrome bd and Gaseous Ligands in Bacterial Physiology", Adv Microb Physiol 71: 171-234.
http://dx.doi.org/10.1016/bs.ampbs.2017.05.002 - S.P. Santos, M.G. Cuypers, A. Round, S. Finet, T. Narayanan, E.P. Mitchell, and C.V. Romão (2017) "SAXS Structural Studies of Dps from Deinococcus radiodurans Highlights the Conformation of the Mobile N-Terminal Extensions", J Mol Biol 429(5): 667-687.
http://dx.doi.org/10.1016/j.jmb.2017.01.008 - A.I. Coelho, E. Rubio-Gozalbo, J.B. Vicente, and I.A. Rivera (2017) "Sweet and sour: "Sweet and sour: an update on classic galactosemia", J Inherit Metab Dis 40(3): 325-342. http://dx.doi.org/10.1007/s10545-017-0029-3
- T.L. Clarke, M.P. Sanchez-Bailon, K. Chiang, J.J. Reynolds, J. Herrero-Ruiz, T.M. Bandeiras, P.M. Matias, S.L. Maslen, J.M. Skehel, G.S. Stewart, and C.C. Davies (2017) "PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination", Mol Cell 65(5): 900-916.e7.
http://dx.doi.org/10.1016/j.molcel.2017.01.019 - J.B. Vicente, H.G. Colaço, F. Malagrinò, P.E. Santo, A. Gutierres, T.M. Bandeiras, P. Leandro, J.A. Brito, and A. Giuffrè (2017) "A clinically relevant variant of the human hydrogen sulfide-synthesizing enzyme cystathionine β-synthase: increased CO reactivity as a novel molecular mechanism of pathogenicity?", Oxid Med Cell Longev 2017: 8940321.
http://dx.doi.org/10.1155/2017/8940321
2016
- E.F. Ruivo, L.M. Gonçalves, L.A. Carvalho, R.C. Guedes, S. Hofbauer, J.A. Brito, M. Archer, R. Moreira and S.D. Lucas (2016) "Clickable 4-Oxo-β-lactam-Based Selective Probing for Human Neutrophil Elastase Related Proteomes", ChemMedChem 11(18): 2037-42
http://dx.doi.org/10.1002/cmdc.201600258 - S.A. Cerqueira, M.Tan, S. Li, F. Juillard, C.E. McVey, K.M. Kaye, J.P. Simas (2016) "LANA E3 Ubiquitin-Ligase Activity Impacts Gammaherpesvirus-Driven Germinal Center B Cell Proliferation", J Virol. 2016 Jun 15.
http://dx.doi.org/10.1128/JVI.00813-16 - J.B. Vicente, F. Malagrinò, M. Arese, E. Forte, P. Sarti, and A. Giuffrè* (2016) " Bioenergetic relevance of hydrogen sulfide and the interplay between gasotransmitters at human cystathionine -synthase", BBA Bioenergetics, in press
http://www.ncbi.nlm.nih.gov/pubmed/27039165 - J.M. Kurth, J.A. Brito, J. Reuter, A. Flegler, T. Koch, T. Franke, E.M. Klein, S.F. Rowe, J.N. Butt, K. Denkmann, I.A. Pereira, M. Archer and C. Dahl (2016) "Electron Accepting Units of the Diheme Cytochrome c TsdA, a Bifunctional Thiosulfate Dehydrogenase/Tetrathionate Reductase", J Biol Chem. 291(48):24804-24818
http://dx.doi.org/10.1074/jbc.M116.753863 - E. Forte, V. Borisov, M. Falabella, H.G. Colaço, M. Tinajero-Trejo, R. Poole, J.B. Vicente, P. Sarti, and A. Giuffrè (2016) "The Terminal Oxidase Cytochrome bd Promotes Sulfide-resistant Bacterial Respiration and Growth", Sci Reports, in press
http://dx.doi.org/10.1038/srep23788 - H.G. Colaço, P.E. Santo, P.M. Matias, T.M. Bandeiras, J.B. Vicente (2016) "Roles of Escherichia coli ZinT in cobalt, mercury and cadmium resistance and structural insights into the metal binding mechanism" Metallomics 8:327-336.
http://dx.doi.org/10.1039/C5MT00291E - C.V. Romão, J.B. Vicente, C. Frazão, and M. Teixeira (2016) "The dual function of flavodiiron proteins: oxygen and/or nitric oxide reductases", J Biol Inorg Chem 21(1): 39-52.
http://dx.doi.org/10.1007/s00775-015-1329-4 - J.B. Vicente, H.G. Colaço, P. Sarti, P. Leandro, and A. Giuffrè* (2016) "S-Adenosyl-L-methionine modulates CO and NO· binding to the human H2S-generating enzyme cystathionine ß-synthase", J Biol Chem 291(2): 572-81.
http://dx.doi.org/10.1074/jbc.M115.681221
2015
- R. Ponnusamy, M.V. Petoukhov, B. Correia, T.F. Custodio, F. Juillard, M. Tan, M. Pires de Miranda, M.A. Carrondo, J.P. Simas, K.M. Kaye, D.I. Svergun, C.E. McVey (2015) "KSHV but not MHV-68 LANA induces a strong bend upon binding to terminal repeat viral DNA." Nucleic Acids Res. 43 (20): 10039-54.
http://dx.doi.org/10.1093/nar/gkv987 - J. A. Brito, K. Denkmann, I. A. C. Pereira, M. Archer, C. Dahl (2015), “Thiosulfate Dehydrogenase (TsdA) from Allochromatium vinosum: Structural and Functional Insights into Thiosulfate Oxidation”, J. Biol. Chem. 290(14):9222-38.
http://dx.doi.org/10.1074/jbc.M114.623397 - • N. Zaarur, X. Xu, P. Lestienne, A.B. Meriin, M. McComb, C.E. Costello, G.P. Newnam, R. Ganti, N.V. Romanova, M. Shanmugasundaram, S.T. Silva, T.M. Bandeiras, P.M. Matias, K.S. Lobachev, I.K. Lednev, Y.O. Chernoff, M.Y. Sherman (2015) “RuvbL1 and RuvbL2 enhance aggresome formation and disaggregate amyloid fibrils” EMBO Journal 112(37):11455-11460.
http://dx.doi.org/10.15252/embj.201591245. - C.M. Sousa, P. Carpentier, P.M. Matias, F. Testa, F. Pinho, P. Sarti, A. Giuffrè, T.M. Bandeiras, C.V. Romão (2015) “Superoxide reductase from Giardia intestinalis: structural characterization of the first SOR from a eukaryotic organism shows an iron centre highly sensitive to photo-reduction” Acta Crystallographica D 71:2236-2247.
http://dx.doi.org/10.1107/S1399004715015825 - Pedersen, H. L., Johnson, K. A., McVey, C. E., Leiros, I. &, Moe E. (2015). “Structure determination of uracil-DNA N-glycosylase from Deinococcus radiodurans in complex with DNA”. Acta Crystallogr D Biol Crystallogr 71: 2137-49
http://dx.doi.org/10.1107/S1399004715014157 - Moe, E., Assefa, N. G., Leiros, I., Torseth, K. J., Smalås, A. O. & Willassen, N. P. (2015). “Reduced Hydrophobicity of the Minor Groove Intercalation Loop is Critical for Efficient Catalysis by Cold Adapted Uracil-DNA N-Glycosylase from Atlantic Cod”. J Thermodyn Catal 6:155
http://dx.doi.org/10.4172/2157-7544.1000155 - A. L. Rosário, F. V. Sena, A. P. Batista, T. F. Oliveira, D. Athayde, M. M. Pereira, J. A. Brito, M. Archer (2015), “Expression, purification, crystallization and preliminary X-ray diffraction analysis of a type II NADH:quinone oxidoreductase from the human pathogen Staphylococcus aureus”, ActaCryst.F 71(4),477-482.
http://dx.doi.org/10.1107/S2053230X15005178 - F. V. Sena, A. P. Batista, T. Catarino, J. A. Brito, M. Archer, M. Viertler, T. Mandl, E. J. Cabrita, M. M. Pereira (2015), “Type-II NADH:quinone oxidoreductase from Staphylococcus aureus has two distinct binding sites and is rate limited by quinone reduction”, Mol. Microbiol. 98(2):272-88.
http://dx.doi.org/10.1111/mmi.13120 - C. G. Fernandes, D. Plácido, D. Lousa, J. A. Brito, A. Isidro, C. M. Soares, J. Pohl, M. A. Carrondo, M. Archer, A. O. Henriques (2015, “Structural and Functional Characterization of an Ancient Bacterial Transglutaminase Sheds Light on the Minimal Requirements for Protein Cross-Linking”, Biochemistry 54(37):5723-34.
http://dx.doi.org/10.1021/acs.biochem.5b00661 - S. Hofbauer, J. A. Brito, J. Mulchande, P. Nogly, M. Pessanha, R. Moreira, M. Archer (2015), “Stabilization of Porcine Pancreatic Elastase (PPE) crystals by glutaraldehyde cross-linking”, ActaCryst.F 71(10),1346-51.
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