Publication List

Since 2000

• Tavares AF, Parente MR, Justino MC, Oleastro M, Nobre LS, Saraiva LM. (2013) The bactericidal activity of carbon monoxide-releasing molecules against Helicobacter pylori. PLoS One. Dec 26;8(12):e83157.
• Justino MC, Ecobichon C, Fernandes AF, Boneca IG, Saraiva LM. (2012) Helicobacter pylori has an unprecedented nitric oxide detoxifying system. Antioxid. Redox Signal. 17, 1190-200.
• Figueiredo MC, Lobo SA, Carita JN, Nobre LS, Saraiva LM. (2012) Bacterioferritin protects the anaerobe Desulfovibrio vulgaris Hildenborough against oxygen. Anaerobe. 18, 454-8.
• Lobo SA, Warren MJ, Saraiva LM. (2012) Sulfate-Reducing Bacteria Reveal a New Branch of Tetrapyrrole Metabolism. Adv Microb Physiol. 61C, 267-295.
• Baptista JM, Justino MC, Melo AMP, Teixeira M, and Saraiva LM. (2012) Oxidative stress modulates the nitric oxide defense promoted by E. coli flavorubredoxin. J. Bacteriol. 194, 3611-7.
• Tavares AF, Nobre LS, Saraiva LM. (2012) A role for reactive oxygen species in the antibacterial properties of carbon monoxide-releasing molecules. FEMS Microbiol Lett. 2012 doi: 10.1111/j.1574-6968.2012.02633.x.
• Bali S, Lawrence AD, Lobo SA, Saraiva LM, Golding BT, Palmer DJ, Howard MJ, Ferguson SJ, Warren MJ. (2011) Molecular hijacking of siroheme for the synthesis of heme and d1 heme. Proc Natl Acad Sci USA. 108, 18260-5.
• Romão C.V, Archer M., Lobo S.A.,Louro R.O., Pereira I.A. C., Saraiva L.M.,Teixeira M. and Matias P.M. (2012) Diversity of Heme Proteins in Sulfate Reducing Bacteria HANDBOOK OF PORPHYRIN SCIENCE - With Applications to Chemistry, Physics, Materials Science, Engineering, Biology and Medicine edited by Kadish K.M., Smith K.M. and Guilard R. 19 (89) pp 139-230, World Scientific Publishing Co. Pte. Ltd., Singapore
• Testa F, Mastronicola D, Cabelli DE, Bordi E, Pucillo LP, Sarti P, Saraiva LM, Giuffrè A, Teixeira M. (2011) The superoxide reductase from the early diverging eukaryote Giardia intestinalis. Free Radic Biol Med. 51, 1567-74.
• Tavares AF, Teixeira M, Romao CC, Seixas JD, Nobre LS, Saraiva LM. (2011) Reactive oxygen species mediate bactericidal kiling elicited by carbon monoxide-releasing molecules. J. Biol Chem. 286, 26708-17.
• Romão CV, Ladakisb D, Lobo SAL,. Carrondo MA, Brindley AA, Deeryb E, Matias PM, Pickersgill MW, Saraiva LM, and Warren MJ (2011) Evolution in a family of chelatases facilitated by the introduction of active site asymmetry and protein oligomerization.. Proc Natl Acad Sci USA.108, 97-102.
• Gonçalves VL, Saraiva LM, and Teixeira M. (2011) Gene expression study of the flavodi-iron proteins from the cyanobacterium Synechocystis sp. PCC6803. Biochem. Soc. Trans. 39, 216-8.
• Todorovic S, Nobre LS, Tavares AFN, Hildebrandt P, Teixeira M, Saraiva LM. (2010) Disentangling interactions of an azole antibiotic with a flavohemoglobin from S. aureus. Proceedings of International conference on Raman spectroscopy. 1267, 873-874.
• Stelter M, Melo AM, Hreggvidsson S, Saraiva LM, Teixeira M, and Archer M. (2010) Structure at 1.0 A resolution of a high-potential iron-sulfur protein involved in the aerobic respiratory chain of Rhodothermus marinus. J. Biol. Inorg. Chem. 15, 303-13.
• Pinho FG, Romão CV, Pinto AF, Saraiva LM, Huber H, Matias PM, Carrondo MA, Teixeira M, and Bandeiras TM (2010) Cloning, purification, crystallization and X-ray crystallographic analysis of Ignicoccus hospitalis neelaredoxin. Acta Crystallogr Sect F Struct Biol Cryst Commun. 66, 605-7.
• Vine CE, Justino MC, Saraiva LM, and Cole J (2010) Detection by whole genome microarrays of a spontaneous 126-gene deletion during construction of a ytfE mutant: confirmation that a ytfE mutation results in loss of repair of iron-sulfur centres in proteins damaged by oxidative or nitrosative stress. J. of Microb. Meth. 81, 77-79.
• Nobre LS, Todorovic S, Tavares AFN, Oldfield P, Hildebrandt P, Teixeira M, and Saraiva, LM (2010) Binding of azole antibiotics to Staphylococcus aureus flavohemoglobin increases intracellular oxidative stress, J. Bacteriol. 192, 1527-33.
• Gonçalves VL, Vicente JB, Saraiva LM and Teixeira M. (2011) Flavodiiron proteins and their role in cyanobacteria, Bioenergetic Processes of Cyanobacteria From Evolutionary Singularity to Ecological Diversity Peschek, Guenter A.; Obinger, Christian; Renger, Gernot (Eds.) 1st Edition., 2011, 500 p., Hardcover ISBN: 978-94-007-0352-0
• Lobo SA, Brindley A, Warren MJ, and Saraiva LM. (2009) Functional characterization of the early steps of tetrapyrrole biosynthesis and modification in Desulfovibrio vulgaris Hildenborough. Biochem J. 420, 317-325.

• Tavares AFN, Nobre LS, Melo AMP, and Saraiva LM. (2009) A novel nitroreductase of Staphylococcus aureus with S-nitrosoglutathione reductase activity. J. Bacteriol. 191, 3403-3406.
• Nobre LS, Al-Shahrour F, Dopazo J, and Saraiva LM. (2009) Exploring the antimicrobial action of a carbon monoxide releasing compound through whole genome transcription profiling of E. coli. Microbiology 155, 813-824.
• Justino MC, Baptista JM and Saraiva LM. (2009) Di-iron proteins of the Ric family are involved in iron-sulfur cluster repair. Biometals 22, 99-108.
• Smutná T, Gonçalves VL, Saraiva LM, Tachezy J, Teixeira M, and Hrdy I. (2009) Flavodiiron protein from Trichomonas vaginalis hydrogenosomes: the terminal oxygen reductase. Eukaryot Cell. 8, 47-55.
• Vicente JB, Ehrenkaufer GM, Saraiva LM, Teixeira M, and Singh U. (2009) Entamoeba histolytica modulates a complex repertoire of novel genes in response to oxidative and nitrosative stress: implications for amebic pathogenesis. Cell Microbiol. 11, 51-69.
• Toussaint L, Cuypers MG, Bertrand L, Hue L, Romão CV, Saraiva LM, Teixeira M, Meyer-Klaucke W, Feiters MC, and Crichton RR. (2009) Comparative Fe and Zn K-edge X-ray absorption spectroscopic study of the ferroxidase centres of human H-chain ferritin and bacterioferritin from Desulfovibrio desulfuricans. J. Biol. Inorg. Chem. 14, 35-49.
• Lobo SA, Almeida CC, Carita JN, Teixeira M, and Saraiva LM. (2008) The haem-copper oxygen reductase of Desulfovibrio vulgaris contains a dihaem cytochrome c in subunit II. Biochim. Biophys. Acta. 1777, 1528–1534.
• Stelter M, Melo AM, Pereira MM, Gomes CM, Hreggvidsson GO, Hjorleifsdottir S, Saraiva LM, Teixeira M, and Archer M. (2008) A novel type of monoheme cytochrome c: biochemical and structural characterization at 1.23A resolution of Rhodothermus marinus cytochrome c. Biochemistry 18, 11953-11963.
• Lobo SAL, Brindley A, Romão CV, Leech H, Warren MJ, and Saraiva LM. (2008) Two distinct roles for two functional cobaltochelatases (CbiK) in Desulfovibrio vulgaris Hildenborough. Biochemistry, 47, 5851-5857.
• Todorovic S, Justino MC, Wellenreuther G, Hildebrandt P, Murgida DH, Meyer-Klaucke W, and Saraiva LM. (2008) Iron-sulfur repair YtfE protein from Escherichia coli: structural characterization of the di-iron center. J. Biol. Inorg. Chem. 13, 765-770.
• Vicente JB, Justino MC, Gonçalves VL, Saraiva LM, and Teixeira M. (2008) Biochemical, spectroscopic and thermodynamic properties of flavodiiron proteins. Meth. in Enzymol. 437, 21-45.
• Nobre LS, Gonçalves VL, and Saraiva LM. (2008) Flavohemoglobin of Staphylococcus aureus. Meth. in Enzymol. 436, 203-216.
• Overton TW, Justino MC, Li Y, Baptista JM, Melo AMP, Cole JA, and Saraiva LM. (2008) Widespread distribution in pathogenic bacteria of di-iron proteins that repair oxidative and nitrosative damage to iron-sulfur centers. J. Bacteriol. 190, 2004-2013.
• Rodrigues JV, Victor BL, Huber H, Saraiva LM, Soares CM, Cabelli DE, and Teixeira M. (2008) Superoxide reduction by Nanoarchaeum equitans neelaredoxin, an enzyme lacking the highly conserved glutamate iron ligand. J. Biol. Inorg. Chem. 13, 219-228.
• Stelter M, Melo AMP, Saraiva LM, Teixeira M, and Archer M. (2007) Crystalization and X-ray analysis of Rhodothermus marinus cytochrome c at 1.23 A resolution. Peptide and Protein Lett. 14, 1038-1040.
• Nobre LS, Seixas JD, Romão CC, and Saraiva LM. (2007) The antimicrobial action of carbon monoxide releasing compounds. Antimicrob. Agents Chemother. 51, 4303-4307.
• Lobo SA, Melo AM, Carita JN, Teixeira M, and Saraiva LM. (2007) The anaerobe Desulfovibrio desulfuricans ATCC 27774 grows at nearly atmospheric oxygen levels. FEBS Lett. 581, 433-436.
• Justino MC, Almeida CC, Teixeira M, and Saraiva LM. (2007) Escherichia coli di-iron YtfE protein is necessary for the repair of stress damaged iron-sulfur clusters. J. Biol. Chem. 282, 10352-10359.
• Rodrigues JV, Saraiva LM, Abreu IA, Teixeira M, and Diane E. Cabelli DE. (2007) Superoxide reduction by Archaeoglobus fulgidus desulfoferrodoxin: comparison with neelaredoxin. J. Biol. Inorg. Chem. 12, 248-256.
• Gomes I, Di Paolo RE, Pereira PM, Pereira IAC, Saraiva LM, Penades S, and Franco R. (2006) Spectroelectrochemistry of type II cytochrome c3 on a glycosylated self-assembled monolayer. Langmuir, 22, 9809-9811.
• Almeida CC, Romao CV, Lindley PF, Teixeira M, and Saraiva LM. (2006) The role of the hybrid-cluster protein in oxidative stress defense. J. Biol Chem. 281, 32445-32450.
• Melo AM, Felix NA, Carita JN, Saraiva LM, and Teixeira M. (2006) The Na+/H+ antiporter of the thermohalophilic bacterium Rhodothermus marinus. Biochem. Biophys. Res. Commun. 348, 1011-1017.
• Valente FMA, Almeida CC, Pacheco I, Carita J, Saraiva LM, and Pereira IAC. (2006) Selenium is involved in regulation of periplasmic hydrogenases gene expression in Desulfovibrio vulgaris Hildenborough. J. Bacteriol. 188, 3228-3235.
• Gonçalves VL, Nobre LS, Vicente JB, Teixeira M, and Saraiva LM. (2006) Flavohemoglobin requires microaerophilic conditions for nitrosative protection of Staphylococcus aureus. FEBS Lett. 580, 1817-1821.
• Justino MC, Almeida CC, Gonçalves VL, Teixeira M, and Saraiva LM. (2006) YtfE is a di-iron protein with an important function in assembly of iron-sulphur clusters. FEMS Microbiol. Lett. 257, 278-284.
• Messias AC, Aguiar AP, Brennan L, Salgueiro CA, Saraiva LM, Xavier AV, and Turner DL. (2006) Solution structures of tetrahaem ferricytochrome c3 from Desulfovibrio vulgaris (Hildenborough) and its K45Q mutant: the molecular basis of cooperativity. Biochim. Biophys. Acta. 1757, 143-153.
• Henriques BJ, Saraiva LM, and Gomes CM. (2006) Combined spectroscopic and calorimetric characterisation of rubredoxin reversible thermal transition. J. Biol. Inorg Chem. 11, 73 – 81.
• Melo AM, Lobo SAL, Sousa FS, Fernandes A, Pereira MM, Hreggvidsson GO, Kristjansson JK, Saraiva LM, and Teixeira M. (2005) A nhaD Na+/H+ antiporter and a pcd homologues are among the Rhodothermus marinus complex I genes. Biochim. Biophys. Acta. 1709, 95-103.
• Henriques BJ, Saraiva LM, and Gomes CM. (2005) Probing the mechanism of rubredoxin thermal unfolding in the absence of salt bridges by temperature jump experiments. Biochem. Biophys. Res. Commun. 333, 839-844.
• Rodrigues JV, Abreu IA, Saraiva LM, and Teixeira M. (2005) Rubredoxin acts as an electron donor for neelaredoxin in Archaeoglobus fulgidus. Biochem. Biophys. Res. Commun. 329, 1300-1305.
• Justino MC, Gonçalves VMM, and Saraiva LM. (2005) Binding of NorR to three DNA sites is essential for promoter activation of the flavorubredoxin gene, the nitric oxide reductase of Escherichia coli. Biochem. Biophys. Res. Commun. 328, 540-544.
• Justino MC, Vicente JB, Teixeira M, and Saraiva LM. (2005) New genes implicated in the protection of anaerobically grown Escherichia coli against nitric oxide. J. Biol. Chem. 280, 2636–2643.
• Srinivasan V, Rajendran C, Sousa FL, Melo AM, Saraiva LM, Pereira MM, Santana M, Teixeira M, Michel H. (2005) Structure at 1.3A resolution of Rhodothermus marinus caa(3) cytochrome c domain. J. Mol. Biol. 345, 1047-1057.
• Correia IJ, Paquete CM, Coelho A, Almeida CC, Catarino T, Louro RO, Frazão C, Saraiva LM, Carrondo MA, Turner DL, and Xavier AV. (2004) Proton assisted two electron transfer in natural variants of tetraheme cytochromes from Desulfomicrobium sp. J. Biol. Chem. 279, 52227-52237.
• Saraiva LM, Vicente JB, and Teixeira M. (2004) The role of the flavodiiron proteins in microbial nitric oxide detoxification. Advances in Microbial Physiology, 49, 77-129.
• Bento I, Matias PM, Baptista AM, Costa PN, van Dongen WMAM, Saraiva LM, Schneider TR, Soares, CM, and Carrondo MA. (2004) Molecular basis for redox-Bohr and cooperative effects in cytochrome c3 from Desulfovibrio desulfuricans ATCC 27774: crystallographic and modelling studies of oxidised and reduced high resolution structures at pH 7.6. Proteins 54, 135-152.
• Miramar MD, Inda LA, Saraiva LM, and Peleato ML. (2003) Plastocyanin/cytochrome c6 interchange in Scenedesmus vacuolatus. Journal Plant Physiology, 160, 1-4.
• Pires RH, Lourenço AI, Morais F, Teixeira M, Xavier AV, Saraiva LM, and Pereira IAC. (2003) A novel membrane-bound respiratory complex from Desulfovibrio desulfuricans ATCC 27774. Biochem. Biophys. Acta 1605, 67-82.
• Aragão D, Macedo S, Mitchell EP, Romão CV, Liu MY, Frazão C, Saraiva LM, Xavier AX, LeGall J, van Dongen WMW, Hagen, WR, Teixeira M, Carrondo MA, and Lindley P. (2003) Reduced Hybrid Cluster Proteins (HCP) from Desulfovibrio desulfuricans ATCC 27774 and Desulfolvibrio vulgaris (Hildenborough). X-ray structures at high resolution using synchrotron radiation. J. Inorg. Biol. Chem. 8, 540-548.
• Costa PN, Teixeira M, and Saraiva LM. (2003) Regulation of the flavorubredoxin nitric oxide reductase gene in Escherichia coli: nitrate repression, nitrite induction, and possible post-transcription control. FEMS Lett. 218, 385-393.
• Abreu IA, Lourenço AI, Xavier AV, LeGall J, Coelho AV, Matias PM, Pinto DM, Carrondo MA, Teixeira M, and Saraiva LM. (2003) A novel iron centre in the split-Soret cytochrome c from Desulfovibrio desulfuricans ATCC 27774. J. Inorg. Biol. Chem. 8, 360-370.
• Pereira MM, Jones KL, Campos MG, Melo AMP, Saraiva LM, Louro RO, Wittung-Stafshede P, and Teixeira M. (2002) A ferredoxin from the thermohalophilic bacterium Rhodothermus marinus. Biochim. Biophys. Acta 1601, 1-8.
• Gomes CM, Giuffrè A, Forte E, Vicente JB, Saraiva LM, Brunori M, and Teixeira M. (2002) A novel type of nitric oxide reductase: Escherichia coli flavorubredoxin. J. Biol. Chem, 277, 25273-25276.
• Valente FMA, Saraiva LM, LeGall J, Xavier AV, Teixeira M, and Pereira IAC (2001) A membrane-bound cytochrome c3 - type II cytochrome c3 from Desulfovibrio vulgaris Hildenborough. ChemBioCHem. 2, 895-905.
• Abreu IA, Saraiva LM, Teixeira M, and Cabelli DE. (2001) The mechanism of superoxide scavenging by Archaeoglobus fulgidus neelaredoxin. J. Biol. Chem. 276, 38995-39001.
• Salgueiro CA, da Costa PN, Messias AC, LeGall J, van Dongen WMAM, Turner D, Saraiva LM, and Xavier AV. (2001) Effect of hydrogen bond networks in controlling redox potentials in Desulfovibrio vulgaris (Hildenborough) cytochrome c3 probed by site specific mutagenesis. Biochemistry 40, 9709-9716.
• Saraiva LM, da Costa PN, Conte C, Xavier AV, and LeGall J. (2001) In the facultative sulfate/nitrate reducer Desulfovibrio desulfuricans ATCC 27774 the nine-heme cytochrome c is part of a membrane-bound redox complex mainly involved in the sulfate respiration. Biochim. Biophys. Acta 1520, 1-8.
• Costa PN, Romão CV, LeGall J, Xavier AV, Melo E, Teixeira M, and Saraiva LM. (2001) The genetic organisation of Desulfovibrio desulfuricans bacterioferritin and rubredoxin genes: involvement of rubredoxin in the iron metabolism. Mol. Microbiol. 41, 217-227.
• Miramar MD, Constantini P, Ravagnan L, Saraiva LM, Haouzi D, Brothers G, Penninger JM, Peleato ML, Kroemer G, and Susin SA. (2001) NADH-oxidase activity of mitochondrial apoptosis-inducing factor (AIF). J. Biol. Chem. 276 , 16391-16398.
• Matias PM, Soares CM, Saraiva LM, Coelho R, Morais J, Le Gall J, and Carrondo MA. (2001) [NiFe] hydrogenase from Desulfovibrio desulfuricans ATCC 27774: gene sequencing, three-dimensional structure determination and refinement at 1.8 Å and modelling studies of its interaction with the tetrahaem cytochrome c3. J. Biol. Inorg. Chem. 6, 63-81.
• Abreu IA, Saraiva LM, Carita J, Huber H, Stetter KO, Cabelli D, and Teixeira M. (2000) Oxygen detoxification in the strict anaerobic archaeon Archaeoglobus fulgidus: superoxide scavenging by neelaredoxin. Mol. Microbiol. 38, 322-334.
• da Costa PN, Marujo P, van Dongen WMA, Arraiano C, and Saraiva LM. (2000) Cloning, sequencing and expression of the tetrahemic cytochrome c3 from Desulfovibrio gigas. Bioch. Biophys. Acta 1492, 271-275.
• da Costa PN, Conte C, and Saraiva LM. (2000) Expression of a Desulfovibrio tetraheme cytochrome c in Escherichia coli. Biochem. Biophys. Res. Commun. 268, 688-691.