Recent Publications

1. J.V. Rodrigues, D. Ruivo, A.Rodríguez, F.J. Deive, J.M.S.S. Esperança, I.M. Marrucho*, C.M. Gomes, L.P.N. Rebelo, Structural-functional evaluation of ionic liquid libraries for the design of co-solvents in lipase-catalysed reactions, accepted in Green Chem DOI: 10.1039/c4gc01329h.

2. C. Florindo, F.S. Oliveira, L. P. N. Rebelo, A.M. Fernandes, I.M. Marrucho*, Insights into the synthesis and properties of deep eutectic solvents based on choline chloride and carboxylic acids, accepted in ACS Chem. Eng. DOI: 10.1021/sc500439w

3. F.S. Oliveira, A.B. Pereiro, J.M.M. Araújo, L.P.N. Rebelo, I.M. Marrucho*, Designing High Ionicity Ionic Liquids based on 1-ethyl-3-methylimidazolium ethylsulfate for Effective Azeotrope Breaking, submitted to AIChE.

4. D.J.S. Patinha, L.C. Tomé, H. Garcia, R. Ferreira, C.S. Pereira, L.P.N. Rebelo, I.M. Marrucho*, The role of water in cholinium carboxylate ionic liquids aqueous solutions, submitted to J. Chem Thermodyn.

5. T. Mourão, L. C. Tome, C. Florindo, L.P.N. Rebelo, I.M. Marrucho*, The role of hydrophilicity in PEG-based aqueous biphasic systems of cholinium carboxylate ionic liquids and salts, accepted in ACS Chem. Eng. DOI : 10.1021/sc500444w

6. F.S. Oliveira, L.P.N. Rebelo and I.M. Marrucho*, Acetate-based High Ionicity Ionic Liquid – Part I. Thermophysical Properties, submitted to J Chem Eng Data.

7. C.M.S.S. Neves, K.A. Kurnia, K. Shimizu, I.M. Marrucho, L.P.N. Rebelo, J.A.P. Coutinho, M.G. Freire, J.N. Canongia Lopes, The impact of ionic liquids fluorinated moieties on their thermophysical properties and aqueous phase behaviour, PCCP 16, 21340-21348, 2014.

8. I.M. Marrucho*, L.C. Branco, L.P.N. Rebelo, Ionic Liquids in Pharmaceutical Applications, Annu. Rev. Chem. Biomol. Eng. 5 : 527–46, 2014. (Invitation)

9. J.M.M. Araujo, C. Florindo, A. B. Pereiro, N. S.M. Vieira, A. Matias, C. M. M. Duarte, L.P.N. Rebelo, I.M. Marrucho*, Cholinium-Based Ionic Liquids with Pharmaceutically Active Anions, RSC Advances 4, 21126-21132, 2014.

10. L.C. Tomé, C. Florindo, C.S.R. Freire, L.P.N. Rebelo, I.M. Marrucho*, Playing with ionic liquid mixtures to design engineered CO2 separation membranes, PCCP 16, 17172-82, 2014.

11. C. Florindo, A. Costa, C. Matos, S.L. Nunes, A. N. Matias, C.M.M. Duarte, L.P.N. Rebelo, L.C. Branco, I.M. Marrucho*, Novel organic salts based on fluoroquinolone drugs: Synthesis, bioavailability and toxicological profiles, Int. J. Pharm. 469, 179-, 2014.

12. N.H.C.S. Silva, C. Varela, I.M. Marrucho, C.S.R. Freire, C.P. Neto, A.J.D. Silvestre, Protein-based materials: from sources to innovative sustainable materials for biomedical applications, J. Mat. Chem. B 2, 3715-3740, 2014.

13. L.C. Tomé, D. Mecerreyes, C.S.R. Freire, L.P.N. Rebelo, I.M. Marrucho*, Polymeric ionic liquid membranes containing IL-Ag+ for ethylene/ethane separation via olefin-facilitated transport, J. Mat. Chem. A 2, 5631-5639, 2014. (feature article)

14. M. Isik, R.Gracia, L.C. Kollnus, L C. Tomé, I. M. Marrucho, D. Mecerreyes, Cholinium-based poly(ionic liquid)s: Synthesis, characterization and application as biocompatible iongels and cellulose coatings, ACS Macro Letters 2 : 975-979, 2013.

15. L.C. Tomé, D.J.S. Patinha, R.Ferreira, H.Garcia, C.S.Pereira, C.S.R. Freire, L.P.N. Rebelo, I.M. Marrucho*, Cholinium-based supported ionic liquid membranes: a sustainable route for CO2 separation, ChemSusChem 7:110-113, 2013.

16. F. S. Oliveira, A.B. Pereiro, J.M.M. Araújo, C.E.S. Bernardes, J.N. Canongia Lopes, S. Todorovic, G. Feio, P.L. Almeida, L.P.N. Rebelo, I.M. Marrucho*, High Ionicity Ionic Liquids (HIILs): Comparing Ethylsulfonate and Ethylsulfate Anion Effect, Phys. Chem. Chem. Phys. 15(41):18138-47, 2013 (highly cited paper, June 2014)

17. C. Florindo, J.M.M. Araújo, F. Alves, C. Matos, R. Ferraz, C. Prudêncio, J.P. Noronha, Z. Petrovski, L. Branco, L.P.N. Rebelo, I.M. Marrucho*, Enhancing Ampicillin Bioavailability and Solubility: an Ionic Liquids Approach, Int. J. Pharm. 456, 553-558, 2013.

18. A.B. Pereiro, M.J. Pastoriza-Gallego, K. Shimizu, I.M. Marrucho, J.N. Canongia Lopes, M. Piñeiro, L.P. Rebelo, On the Formation of a Third, Nanostructured Domain in Ionic Liquids, J.Phys. Chem B. 117 , 10826–10833, 2013.

19. C.M.S.S. Neves, K. A. Kurnia, J.A.P. Coutinho, I.M. Marrucho, J.N. Canongia Lopes, M.G. Freire, L.P.N. Rebelo, Systematic Study of the Thermophysical Properties of Imidazolium-Based Ionic Liquids with Cyano-Functionalized Anions, J. Phys. Chem. B 117, 10271−10283, 2013.
20. L.C. Tomé, M. A. Aboudzadeh, L.P.N. Rebelo, C.S.R. Freire, D. Mecerreyes, I.M. Marrucho*, Polymeric ionic liquids with mixtures of counter-anions: new straightforward strategy for designing pyrrolidinium-based CO2 separation membranes, J. Mater. Chem. A, 1, 10403 – 10411, 2013.
21. L.C. Tomé, D.J.S. Patinha, C.S.R. Freire, L.P.N. Rebelo, I.M. Marrucho*, CO2 separation applying ionic liquid mixtures: the effect of mixing different anions on gas permeation through supported ionic liquid membranes, RSC Advances 3, 12220-12229, 2013.
22. A.B. Pereiro, L. C. Tomé, S. Martinho, L.P.N. Rebelo, I. M. Marrucho*, Gas Permeation Properties of Fluorinated Ionic Liquids, Ind. Eng. Chem Res. 52, 4994-5001, 2013.
23. J. M. M. Araújo, A.B. Pereiro, J.N. Canongia Lopes, L.P.N. Rebelo and I. M. Marrucho*, Hydrogen-Bonding and the Dissolution Mechanism of Uracil in an Acetate Ionic Liquid: New Insights from NMR Spectroscopy and Quantum Chemical Calculations, J. Phys. Chem B. 117, 4109-4120, 2013.
24. S. Martinho, J.M.M. Araújo, L.P.N. Rebelo, A. B. Pereiro, I. M. Marrucho*, Liquid-liquid Equilibria of Perfluorocarbons with Fluorinated Ionic Liquids, J. Chem. Thermodyn. 64, 71-79, 2013.
25. B.D. Ribeiro, M.A. Z. Coelho, I.M. Marrucho*, Extraction of Saponins from Sisal (Agave sisalana) and Jua (Ziziphus joazeiro) with Cholinium-based Ionic Liquids and Deep Eutectic Solvents, Eur. J. Food Technol. 237, 956-975, 2013.
26. B. D. Ribeiro, M.A. Z. Coelho, I.M. Marrucho*, Use of Ionic Liquids for Extraction of Saponins from Mate (Ilex Paraguriensis) and Tea (Camellia Sinenis) Ind. Eng. Chem. Res. 52, 12146−12153, 2013.

27. F.S. Oliveira, A.B. Pereiro, L.P.N. Rebelo, I.M. Marrucho*, Deep Eutectic Solvents as Extraction Solvents for Azeotropic Mixtures, Green Chem. 15, 326-330, 2013.
28. D.J.S. Patinha, F. Alves, F.J. Deive, A. Rodriguez, L.P.N. Rebelo, I.M. Marrucho*, Ionic Liquids Based Aqueous Biphasic Systems: Effect of the position of the alkyl chains - cation versus anion, J. Chem. Thermodyn. 65, 106-112, 2013.
29. F. Alves, F.S. Oliveira, B. Schroder, C. Matos, I.M. Marrucho*, Synthesis, characterization, and liposome partition of a novel tetracycline derivative using the ionic liquids framework, J. Pharm. Sci. 102, 1504-1512, 2013.
30. A.B. Pereiro, J.M.M. Araújo, S. Martinho, F. Alves, A. Matias, S. Nunes, C.M.M. Duarte, L.P.N. Rebelo, I.M. Marrucho*, Fluorinated Ionic Liquids: Properties and Applications, ACS Sutainable Chemistry & Engineering 1, 427-439, 2013.
31. C.M.B. Gonçalves, L.C. Tomé, L. Brandão, A. M. Mendes, I.M. Marrucho*, Effect of natural and synthetic antioxidants incorporation on the gas permeation properties of poly(lactic acid) films, J. Food Eng 116, 562-571, 2013.
32. S. Shahriari, L.C. Tomé, J.M.M. Araújo, L.P.N. Rebelo, J.A.P. Coutinho, I.M. Marrucho*, Mara G. Freire, Aqueous Biphasic Systems: A Novel Route using Biocompatible Choline-Based Ionic Liquids, RSC Advances 3, 1835-1843, 2013.
33. L.C. Tomé, D. Mecerreyes, C.S.R. Freire, L.P.N. Rebelo, I.M. Marrucho*, Pyrrolidinium-based polymeric ionic liquid materials: new perspectives for CO2 separation membranes, J. Memb. Sci. 428, 260-266, 2013. (highly cited paper, top 1%)
34. A. Bhattacharjee, C. Varanda, M.G. Freire, S. Matted, L.M.N.B.F. Santos, I.M. Marrucho*, J.A.P. Coutinho, Density and viscosity data for binary mixtures of 1-alkyl-3-methylimidazolium alkylsulfates + water, J. Chem. Eng. Data 57, 3473−3482, 2012.
35. J. M. M. Araújo, A. B. Pereiro, F. Alves, I. M. Marrucho*, L. P. N. Rebelo, Nucleic acid bases in 1-alkyl-3-methylimidazolium acetate ionic liquids: a thermophysical and ionic conductivity analysis, J. Chem. Thermodyn. 57, 1-8, 2013.

36. R. Leones, F. Sentanin, L. C. Rodrigues, I. M. Marrucho, J. M. S. S. Esperança, A. Pawlicka,M. M. Silva, Investigation of polymer electrolyte based on agar and ionic liquids, eXpress polymer Lett. 6, 1007-1016, 2012.

37. R. Leones, F. Sentanin, L. C. Rodrigues, R.A. Ferreira, I. M. Marrucho, J. M. S. S. Esperança, A. Pawlicka, L.D. Carlos, M. M. Silva, Novel polymer electrolyte based on gelatin and ionic liquids, OPTMAT 35, 127-135, 2012.
38. M.G. Freire, A.F.M. Cláudio, J.M.M. Araújo, J.A.P. Coutinho, I.M. Marrucho, J.N. Canongia Lopes, L.P.N. Rebelo, Aqueous Biphasic Systems: A boost brought about by using ionic liquids, Chem. Soc. Rev. 41, 4966-4995, 2012. (highly cited paper, top1%)
39. M.G. Freire, A.R.R. Teles, J.N.C. Lopes, L.P.N. Rebelo, I.M. Marrucho*, J.A.P. Coutinho, Partition Coefficients of Alkaloids in Biphasic Ionic-Liquid-Aqueous Systems and their Dependence on the Hofmeister Series, Sep. Pur. Techn. 47, 284-291, 2012.
40. A.M.A. Dias, S. Marceneiro, M.E.M. Braga, J.F.J. Coelho, A.G.M. Ferreira, P.N. Simões, H.I.M. Veiga, L.C. Tomé, I.M. Marrucho, J.M.S.S. Esperança. A.A. Matias, C.M.M. Duarte, L.P.N. Rebelo, H.C. Sousa, Phosphonium-based ionic liquids as modifiers for biomedical grade poly(vinyl chloride) , Acta Biomaterialia 8, 1366-1379, 2012.

41. A.J.L. Costa, M.R.C. Soromenho, K. Shimizu, I.M. Marrucho, J.M.S.S. Esperança, J.N. Canongia Lopes, L.P.N. Rebelo, Liquid−Liquid Equilibrium of Cholinium-Derived Bistriflimide Ionic Liquids with Water and Octanol, J.Phys. Chem B., 116, 9186-9195, 2012.

42. A. B. Pereiro, J. M. M. Araújo, F. S. Oliveira, J. M. S. S. Esperança, J. N. Canongia Lopes, I. M. Marrucho, L. P. N. Rebelo, Solubility of Inorganic Salts in Pure Ionic Liquids, J. Chem. Thermodyn. 55, 29-36, 2012.

43. M.G. Freire, C.M.S.S. Neves, J.N. Canongia Lopes, I.M. Marrucho, J. A. P. Coutinho, L.P.N. Rebelo, Impact of Self-Aggregation on the Formation of Ionic-Liquid-Based Aqueous Biphasic Systems, J.Phys. Chem B. 116, 7660-7668, 2012.

44. R. Ferraz, LC. Branco, I.M. Marrucho*, J.M.M. Araújo, L.P.N. Rebelo, M. N. Ponte, C. Prudêncio, J.P. Noronha, Z. Petrovski, Development of novel ionic liquids based on ampicillin, Med. Chem. Comm., 3, 494-497, 2012.

45. F.J. Deive, A. Rodríguez, L.P.N. Rebelo, I.M. Marrucho*, Extraction of Candida antarctica lipase A from aqueous solutions using imidazolium-based ionic liquids, Sep. Pur. Technol., 97, 205-201, 2012.

46. A.J.L. Costa, M.R.C. Soromenho, K. Shimizu, I.M. Marrucho*, J.M.S.S. Esperança, J.N. Canongia Lopes, L.P.N. Rebelo. Density, Thermal Expansion and Viscosity of Cholinium- Derived Ionic Liquids, Chem Phys Chem 13, 1902-1909, 2012.

47. A.B. Pereiro, J.M.M. Araújo, F.S. Oliveira, C.E.S. Bernardes, J.M. S.S. Esperança, J.N. Canongia Lopes, I.M. Marrucho and L.P.N. Rebelo, Inorganic Salts in Purely Ionic Liquid Media: The Development of High Ionicity Ionic Liquids (HIILs), Chem. Comm. 46, 3656-3658, 2012.

48. F. S. Oliveira, J. M.M. Araújo, R. Ferreira, L. P. N. Rebelo, I. M. Marrucho*, Extraction of L-lactic, L-malic, and succinic acids using phosphonium-based ionic liquids, Sep. Pur. Technol. 85, 137-146, 2012.

49. A. B. Pereiro, J. M. M. Araújo, J. M. S. S. Esperança, I. M. Marrucho, L. P. N. Rebelo, Ionic Liquids in Separations of Azeotropic Systems  A Review, J. Chem. Thermodyn. 46, 2-28, 2012 (invited) (highly cited paper, top1%)