Publications
2021
Bárbara B. Sousa, Marcos F. Q. Sousa, Marta C. Marques, João D. Seixas, José A. Brito, Pedro M. Matias, Gonçalo J. L. Bernardes, António Roldão, “A scalable insect cell-based production process of the human recombinant BMX for in-vitro covalent ligand high-throughput screening” (2021), Bioprocess Biosyst Eng 44(1):209-215
2020
José A. Brito and Margarida Archer, “Chapter 10: Structural Biology Techniques: X-ray Crystallography, Cryo-Electron Microscopy, and Small-Angle X-ray Scattering” (2020) in “Practical Approaches to Biological Inorganic Chemistry (Second Edition)”, Ricardo Louro and Robert Crichton (eds.), Elsevier (Oxford, UK).
Luís A. R. Carvalho*, Vanessa Almeida*, José A. Brito, K. Lum, L. M. Gonçalves, Susana D. L. Lucas, B, Cravatt, Margarida Archer, Rui Moreira, “3-Oxo-β-Sultam as a Sulfonylating Chemotype for Inhibition of Serine Hydrolases and Activity-Based Profiling” (2020), ACS Chem Biol 15:878−883
2019
Brenna J. Walsh, José A. Brito, David P. Giedroc, “Hydrogen Sulfide Signaling and Enzymology” (2019) in “Comprehensive Natural Products III: Chemistry and Biology”, Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, Elsevier (Oxford, UK).
2018
Sara T.N. Silva, José A. Brito, Rocío Arranz, Carlos Óscar S. Sorzano, Christine Ebel, James Doutch, Mark D. Tully, José-María Carazo, José L. Carrascosa, Pedro M. Matias, Tiago M. Bandeiras, “X-ray structure of full-length human RuvB-Like 2 – mechanistic insights into coupling between ATP binding and mechanical action” (2018), Sci Rep 8:13726
2017
F. M. Sousa, F. V. Sena, A. P. Batista, D. Athayde, José A. Brito, M. Archer, A. S. F. Oliveira, C. M. Soares, T. Catarino, M. M. Pereira, "The key role of glutamate 172 in the mechanism of type II NADH:quinone oxidoreductase of Staphylococcus aureus" (2017), Biochim Biophys Acta 1858(10):823-832.
João B. Vicente, Henrique G. Colaço, Francesca Malagrinò, Paulo E. Santo, André Gutierres, Tiago M. Bandeiras, Paula Leandro, José A. Brito, Alessandro Giuffré, “A clinically relevant variant of the human hydrogen sulfide-synthesizing enzyme cystathionine β-synthase: increased CO reactivity as a novel molecular mechanism of pathogenicity?” (2017), Oxid. Med. Cel. Long., Special Issue on "Modulation of Oxidative Stress: Pharmaceutical and Pharmacological Aspects 2017", 2017:8940321.
2016
Julia M. Kurth*, José A. Brito*, Jula Reuter, Alexander Flegler, Tobias Koch, Thomas Franke, Eva-Maria Klein, Sam F. Rowe, Julea N. Butt, Kevin Denkmann, Inês A.C. Pereira, Margarida Archer, Christiane Dahl, “Electron Accepting Units of the Diheme Cytochrome c TsdA, a Bifunctional Thiosulfate Dehydrogenase/Tetrathionate Reductase” (2016), J. Biol. Chem. 291 (48):24804-24818.
Eduardo F. P. Ruivo, Lídia M. Gonçalves, Luís A. R. Carvalho, Rita C. Guedes, Stefan Hofbauer, José A. Brito, Margarida Archer, Rui Moreira, Susana D. Lucas, “Clickable `4-oxo-β-lactam-based probe for human neutrophil elastase related proteomes” (2016), Chem. Med. Chem. 11(18), 2037-42.
2015
Stefan Hofbauer, José A. Brito, Jalmira Mulchande, Przemyslaw Nogly, Miguel Pessanha, Rui Moreira, Margarida Archer, “Stabilization of porcine pancreatic elastase crystals by glutaraldehyde cross-linking” (2015), Acta Cryst. F71 (10), 1346-51
Catarina G. Fernandes, Diana Plácido, Diana Lousa, José A. Brito, Anabela Isidro, Cláudio M. Soares, Jan Pohl, Maria A. Carrondo, Margarida Archer and Adriano O. Henriques, “Structural and Functional Characterization of an Ancient Bacterial Transglutaminase Sheds Light on the Minimal Requirements for Protein Cross-Linking” (2015), Biochemistry 54(37):5723-34
Filipa V. Sena, Ana P. Batista, Teresa Catarino, José A. Brito, Margarida Archer, Martin Viertler, Tobias Mandl, Eurico J. Cabrita, Manuela M. Pereira, “Type-II NADH:quinone oxidoreductase from Staphylococcus aureus has two distinct binding sites and is rate limited by quinone reduction” (2015), Mol. Microbiol. 98(2):272-88
Ana Lúcia Rosário, Filipa V. Sena, Ana P. Batista, Tânia F. Oliveira, Diogo Athayde, Manuela M. Pereira, José A. Brito, Margarida Archer, “Expression, purification, crystallization and preliminary X-ray diffraction analysis of a type II NADH:quinone oxidoreductase from the human pathogen Staphylococcus aureus” (2015), Acta Cryst. F71 (4), 477-82.
José A. Brito, Kevin Denkmann, Inês A. C. Pereira, Margarida Archer and C. Dahl, “Thiosulfate Dehydrogenase (TsdA) from Allochromatium vinosum: Structural and Functional Insights into Thiosulfate Oxidation” (2015), J. Biol. Chem. 290 (14):9222-38.
2014
José A. Brito, André Gutierres, Kevin Denkmann, Inês C. Pereira, Christianne Dahl and Margarida Archer, “Production, crystallization and preliminary crystallographic analysis of Allochromatium vinosum TsdA, an unusual acidophilic c-type cytochrome” (2014), Acta Cryst. F70:1424-27.
2013
Pikyee Ma, Filipa Varela, Malgorzata Magoch, Ana Rita Silva, Ana Lúcia Rosário, José A. Brito, Tânia F. Oliveira, Przemyslaw Nogly, Miguel Pessanha, Meike Stelter, Peter J.F. Henderson, Arnulf Kletzin and Margarida Archer, "An efficient strategy for small-scale screening and production of archaeal membrane transport proteins in Escherichia coli" (2013), PLoS ONE 8(10):e76913
José A. Brito and Margarida Archer, “Chapter 9: X-ray Crystallography” (2013) in “Practical approaches to biological inorganic chemistry”, Ricardo Louro and Robert Crichton (eds.), Elsevier (Oxford, UK).
2011
José A. Brito, Nuno Borges, Clemens Vonrhein, Helena Santos and Margarida Archer, “Crystal structure of Archaeoglobus fulgidus CTP:Inositol-1-Phosphate Cytidylyltransferase, a key enzyme for Di-myo-Inositol-Phosphate synthesis in (Hyper)thermophiles” (2011), J. Bacteriol. 193(9), 2177-85.
2010
José A. Brito, Nuno Borges, Helena Santos and Margarida Archer, “Production, crystallization and preliminary X-ray analysis of CTP:inositol-1-phosphate cytidylyltransferase from Archaeoglobus fulgidus” (2010), Acta Cryst. F66 (11), 1463-65.
2009
José A. Brito*, Filipa F. Sousa*, Meike Stelter, Tiago M. Bandeiras, Clemens Vonrhein, Miguel Teixeira, Manuela M. Pereira and Margarida Archer (2009), Structural and functional insights into sulfide:quinone oxidoreductase, Biochemistry 48(24), 5613-22.
2006
José A. Brito, Tiago M. Bandeiras, Miguel Teixeira, Clemens Vonrhein and Margarida Archer (2006), Crystallization and preliminary structure determination of NADH:quinone oxidoreductase from the extremophile Acidianus ambivalens, Biochim Biophys Acta (BBA) – Proteins and Proteomics 1764(4), 842-5
