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Publications

               
Papers in peer review journals
  1. G. Elif Karagöz, Afonso M.S. Duarte, Elias Akoury, Hans Ippel, Jacek Biernat, Tania Morán Luengo, Martina Radli, Tatiana Didenko, Bryce A. Nordhues, Dmitry B. Veprintsev, Chad A. Dickey, Eckhard Mandelkow, Markus Zweckstetter, Rolf Boelens, Tobias Madl, Stefan G.D. Rüdiger, Hsp90-Tau Complex Reveals Molecular Basis for Specificity in Chaperone Action. Cell, 2014,Volume 156, Issue 5, 963-974. 
  2. Bruno C. Marreiros;  Ana P. Batista; Afonso M. S. Duarte; Manuela M. Pereira "A missing link between complex I and group 4 membrane-bound [NiFe]-hydrogenases". Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2013, 1827, 2, 198-209.
  3. Suijkerbuijk SJE, Van Dam TJP, Karagöz GE, Von Castelmur E, Hubner NC, Afonso M.S. Duarte, Vleugel M, Perrakis A, Rüdiger SGD, Snel B, Kops GJPL. The vertebrate mitotic checkpoint protein BUBR1 is an unusual pseudokinase. Developmental Cell, 2012, 22, 6, 1321-1329.
  4. Yanyan Li, G. Elif Karagöz, Young Ho Seo, Tao Zhang, Yiqun Jiang, Yanke Yu, Afonso M.S. Duarte, Steven J. Schwartz, Rolf Boelens, Kate Carroll, Stefan G.D. Rüdiger, and Duxin Sun "Sulforaphane inhibits pancreatic cancer through disrupting Hsp90–p50Cdc37 complex and direct interactions with amino acids residues of Hsp90" The Journal of Nutritional Biochemistry, 2012 32, 12, 1617-1626.
  5. Tatiana Didenko, Afonso M.S. Duarte, G. Karagöz, Stefan G.D. Rüdiger "Hsp90 structure and function studied by NMR spectroscopy",Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2012, 1823, 3, 636–647
  6. G. Karagöz* , Afonso M.S. Duarte* , Johannes Ippel , Charlotte Uetrecht , Tessa Sinnige , Martijn van Rosmalen , Jens Hausmann , Albert Heck , Rolf Boelens , Stefan G.D. Rüdiger “The N-terminal domain of human Hsp90 triggers binding to the co-chaperone p23”, PNAS, 2011, 108, 580-585. ( *joint first co-authorship)
  7. Maria Noutsou, Afonso M.S. Duarte, Zeinab Anvarian, Tatiana Didenko, David P. Minde, Ineke Kuper, Isabel de Ridder, Christina Oikonomou, Assaf Friedler, Rolf Boelens, Stefan G.D. Rüdiger, Madelon M Maurice “Critical Scaffolding Regions of the Tumor Suppressor Axin1 are Natively Unfolded”, JMB, 2011, 405, 3, 773-786.
  8. Afonso M.S. Duarte, Edwin R. de Jong, Rob B. M. Koehorst and Marcus A. Hemminga, “Conformational studies of peptides representing a segment of TM7 from VO-H+-V-ATPase in SDS micelles”, Eur. Biophys. J. 2010,39, 639–646. 
  9. Afonso M. S. Duarte, Carlo P. M. van Mierlo, Marcus A. Hemminga “Molecular dynamics study of the solvation of an α-helical transmembrane peptide by DMSO”, Journal of Physical Chemistry B, 2008 112 (29), 8664-8671. 
  10. Afonso M.S. Duarte, Cor J. A. M. Wolfs, Rob B. M. Koehorst, Jean-Luc Popot, Marcus A. Hemminga “Solubilization of V‑ATPase transmembrane peptides by amphipol A8‑35”, Journal of peptide science 14, 2008, 389-393.
  11. Afonso M. S. Duarte, Edwin R. de Jong, Rainer Wechselberger, Carlo P. M. van Mierlo, Marcus A. Hemminga “Segment TM7 from the cytoplasmic hemi-channel from VO-H+-V-ATPase includes a flexible region that has a potential role in proton translocation”, Biochimica et Biophysica Acta (BBA) - Biomembranes, 2007, 1768, 9, 2263-2270.
  12. Afonso M. S. Duarte, Cor J. A. M. Wolfs, Nico A. J. van Nuland, Michael A. Harrison, John B. C. Findlay, Carlo P. M. van Mierlo, Marcus A. Hemminga “Structure and localization of an essential transmembrane segment of the proton translocation channel of yeast H+-V-ATPase”Biochimica et Biophysica Acta (BBA) - Biomembranes, 2007, 1768, 2, 218-227. 

 
Book chapter
 
  1. Afonso M.S. Duarte and Marcus A. Hemminga, "Tracking down a new putative drug target for osteoporosis: Structure of an essential region of the proton translocation channel of H+-VO-ATPase", in Antibiotic Resistance: Causes and Risk Factors, Mechanisms and Alternatives, Columbus, F., Ed., Nova Science Publishers, Hauppauge, New York, USA (2009), pp. 345-369, ISBN 978-1-60741-623-4.
 
 
Theses

Oral presentations
  •  Keynote Speaker in the European Grid Infrastructure Technical forum, August 2013,  Madrid, Spain (invited lecture)
  • European Magnetic Resoance Meeting (EUROMAR), 2010, Florence, Italy;
  • Annual meeting of the Chaperone Dutch Group, 2009, Nijmegen, The Netherlands;
  • Annual meeting of the Dutch Protein Group, December 2009, Veldhoven, The Netherlands;
  • Annual meeting of the Dutch Protein Group, December 2006, Lunteren, The Netherlands;
  • Symposium of the 3rd Theme from EPS School, November 2006, Amsterdam, The Netherlands;
  • Annual meeting of the Dutch Biophysics Group, October 2006, Lunteren, The Netherlands;
  • Annual meeting of the Dutch NMR group (NMR-DG), October 2006, Oss, The Netherlands;
  • Annual meeting of the Dutch Molecular Membranes Group, March 2006, Lunteren, The Netherlands



 

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